Search Results
Overview
| Uniprot ID | Q8WYR4 |
|---|---|
| Protein Name | Radial spoke head 1 homolog |
| Gene Name | RSPH1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 162 | LNHRYQGKFLNKNPV |
| 166 | YQGKFLNKNPVGPGK |
Function
Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia
Protein Sequence
10
MSDLGSEELE
20
EEGENDIGEY
30
EGGRNEAGER
40
HGRGRARLPN
50
GDTYEGSYEF
60
GKRHGQGIYK
70
FKNGARYIGE
80
YVRNKKHGQG
90
TFIYPDGSRY
100
EGEWANDLRH
110
GHGVYYYINN
120
DTYTGEWFAH
130
QRHGQGTYLY
140
AETGSKYVGT
150
WVNGQQEGTA
160
ELIHLNHRYQ
170
GKFLNKNPVG
180
PGKYVFDVGC
190
EQHGEYRLTD
200
MERGEEEEEE
210
ELVTVVPKWK
220
ATQITELALW
230
TPTLPKKPTS
240
TDGPGQDAPG
250
AESAGEPGEE
260
AQALLEGFEG
270
EMDMRPGDED
280
ADVLREESRE
290
YDQEEFRYDM
300
DEGNINSEEE
ETRQSDLQD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0097729 | 9+2 motile cilium |
| Cellular Component | GO:0005930 | axoneme |
| Cellular Component | GO:0005929 | cilium |
| Cellular Component | GO:0000794 | condensed nuclear chromosome |
| Cellular Component | GO:0072687 | meiotic spindle |
| Cellular Component | GO:0031514 | motile cilium |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0001520 | outer dense fiber |
| Cellular Component | GO:0001535 | radial spoke head |
| Cellular Component | GO:0120336 | radial spoke head 1 |
| Cellular Component | GO:0120338 | radial spoke head 3 |
| Cellular Component | GO:0036126 | sperm flagellum |
| Biological Process | GO:0035082 | axoneme assembly |
| Biological Process | GO:0003341 | cilium movement |
| Biological Process | GO:0030317 | flagellated sperm motility |
| Biological Process | GO:0051321 | meiotic cell cycle |
| Biological Process | GO:0007286 | spermatid development |
Reference
[1] Yan M, Tu H, Tang S, Gai Z, Shi Q et al.. Lactylated Proteomic Analysis Reveals Functional Implications of Lysine Lactylation In Asthenozoospermia.. Mol Cell Proteomics 24(12):101439. 2025 Dec. PMID: 41192556.