Search Results
Overview
| Uniprot ID | Q91ZE0 |
|---|---|
| Protein Name | Trimethyllysine dioxygenase, mitochondrial |
| Gene Name | Tmlhe |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 236 | RGDTAYTKLALDRHT |
Function
Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML) in the carnitine biosynthesis pathway
Protein Sequence
10
MWYHKLLHQQ
20
SRLRNLMKRG
30
NIAQGLHLSN
40
FKSLFSSSIH
50
WCHTTSKSVN
60
CTWHQHEDHL
70
ELQYAGTVMR
80
FDYVWLRDHC
90
RSASCYNSKT
100
HQRSLDTASV
110
DLCIKPKTVH
120
LDETMLFFTW
130
PDGHVTRYDL
140
DWLVKNSYEG
150
QKQKVIQPRI
160
LWNSKLYQQA
170
QVPSVDFQCF
180
LETNEGLKKF
190
LQNFLLYGIA
200
FVENVPPTEE
210
HTEKLAERIS
220
LIRETIYGRM
230
WYFTSDFSRG
240
DTAYTKLALD
250
RHTDTTYFQE
260
PCGIQVFHCL
270
KHEGTGGRTL
280
LVDGFYAAQQ
290
VLQKAPEEFE
300
LLSKVPLKHE
310
YIENVGQCHN
320
HMIGVGPILN
330
IYPWNKELYL
340
IRYNNYDRAV
350
INTVPYDVVH
360
RWYTAHRTLT
370
TELRRPENEL
380
WVKLKPGKVL
390
FIDNWRVLHG
400
RESFTGYRQL
410
CGCYLTRDDV
420
LNTARLLGLH
A
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005759 | mitochondrial matrix |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0005506 | iron ion binding |
| Molecular Function | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
| Molecular Function | GO:0050353 | trimethyllysine dioxygenase activity |
| Biological Process | GO:0045329 | carnitine biosynthetic process |
Reference
[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.