Search Results
Overview
| Uniprot ID | Q921G7 |
|---|---|
| Protein Name | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial |
| Gene Name | Etfdh |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 131 | KELFPDWKEKGAPLN |
| 133 | LFPDWKEKGAPLNTP |
| 152 | RFAILTEKHRIPVPI |
| 222 | TNDVGIQKDGAPKTT |
| 283 | ELWIIDEKKWKPGRV |
| 356 | QPTLEGGKRIAYGAR |
| 496 | GSDSDQLKPAKDCTP |
| 87 | LSAAIRLKQLAAEQG |
| 95 | QLAAEQGKDIRVCLV |
Function
Links fatty acid beta-oxidation and amino acid catabolism to the respiratory chain by transferring electrons from the electron transfer flavoprotein (ETF) to ubiquinone
Protein Sequence
10
MLVRLTKLSC
20
PAYHWFHALK
30
IKKCLPLCAP
40
RCSSTSAVPQ
50
ITTHYTVHPR
60
EKDKRWEGVN
70
MERFAEEADV
80
VIVGAGPAGL
90
SAAIRLKQLA
100
AEQGKDIRVC
110
LVEKAAQIGA
120
HTLSGACLDP
130
AAFKELFPDW
140
KEKGAPLNTP
150
VTEDRFAILT
160
EKHRIPVPIL
170
PGLPMNNHGN
180
YIVRLGHLVS
190
WMGEQAEALG
200
VEVYPGYAAA
210
EVLYHEDGSV
220
KGIATNDVGI
230
QKDGAPKTTF
240
ERGLELHAKV
250
TVFAEGCHGH
260
LAKQLYKKFD
270
LRASCDAQTY
280
GIGLKELWII
290
DEKKWKPGRV
300
DHTVGWPLDR
310
HTYGGSFLYH
320
LNEGEPLVAV
330
GFVVGLDYQN
340
PYLSPFREFQ
350
RWKHHPSIQP
360
TLEGGKRIAY
370
GARALNEGGL
380
QSIPKLTFPG
390
GLLIGCSPGF
400
MNVPKIKGTH
410
TAMKSGSLAA
420
ESIFKQLTSE
430
NLQSKTTGLH
440
VTEYEDNLKQ
450
SWVWKELHAV
460
RNIRPSCHGI
470
LGVYGGMIYT
480
GIFYWILRGM
490
EPWTLKHKGS
500
DSDQLKPAKD
510
CTPIEYPKPD
520
GQISFDLLSS
530
VALSGTNHEH
540
DQPAHLTLKD
550
DSIPVNRNLS
560
IYDGPEQRFC
570
PAGVYEFVPL
580
EQGDGFRLQI
590
NAQNCVHCKT
600
CDIKDPSQNI
610
NWVVPEGGGG
PAYNGM
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0017133 | mitochondrial electron transfer flavoprotein complex |
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0031966 | mitochondrial membrane |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0051539 | 4 iron, 4 sulfur cluster binding |
| Molecular Function | GO:0009055 | electron transfer activity |
| Molecular Function | GO:0004174 | electron-transferring-flavoprotein dehydrogenase activity |
| Molecular Function | GO:0051536 | iron-sulfur cluster binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0016491 | oxidoreductase activity |
| Molecular Function | GO:0048038 | quinone binding |
| Molecular Function | GO:0048039 | ubiquinone binding |
| Biological Process | GO:0022900 | electron transport chain |
| Biological Process | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase |
| Biological Process | GO:0006979 | response to oxidative stress |
Reference
[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.
[2] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.