Search Results
Overview
| Uniprot ID | Q921I1 |
|---|---|
| Protein Name | Serotransferrin |
| Gene Name | Tf |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 315 | LGKDLLFKDSAFGLL |
Function
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation
Protein Sequence
10
MRLTVGALLA
20
CAALGLCLAV
30
PDKTVKWCAV
40
SEHENTKCIS
50
FRDHMKTVLP
60
PDGPRLACVK
70
KTSYPDCIKA
80
ISASEADAMT
90
LDGGWVYDAG
100
LTPNNLKPVA
110
AEFYGSVEHP
120
QTYYYAVAVV
130
KKGTDFQLNQ
140
LEGKKSCHTG
150
LGRSAGWVIP
160
IGLLFCKLSE
170
PRSPLEKAVS
180
SFFSGSCVPC
190
ADPVAFPKLC
200
QLCPGCGCSS
210
TQPFFGYVGA
220
FKCLKDGGGD
230
VAFVKHTTIF
240
EVLPEKADRD
250
QYELLCLDNT
260
RKPVDQYEDC
270
YLARIPSHAV
280
VARKNNGKED
290
LIWEILKVAQ
300
EHFGKGKSKD
310
FQLFSSPLGK
320
DLLFKDSAFG
330
LLRVPPRMDY
340
RLYLGHNYVT
350
AIRNQQEGVC
360
PEGSIDNSPV
370
KWCALSHLER
380
TKCDEWSIIS
390
EGKIECESAE
400
TTEDCIEKIV
410
NGEADAMTLD
420
GGHAYIAGQC
430
GLVPVMAEYY
440
ESSNCAIPSQ
450
QGIFPKGYYA
460
VAVVKASDTS
470
ITWNNLKGKK
480
SCHTGVDRTA
490
GWNIPMGMLY
500
NRINHCKFDE
510
FFSQGCAPGY
520
EKNSTLCDLC
530
IGPLKCAPNN
540
KEEYNGYTGA
550
FRCLVEKGDV
560
AFVKHQTVLD
570
NTEGKNPAEW
580
AKNLKQEDFE
590
LLCPDGTRKP
600
VKDFASCHLA
610
QAPNHVVVSR
620
KEKAARVKAV
630
LTSQETLFGG
640
SDCTGNFCLF
650
KSTTKDLLFR
660
DDTKCFVKLP
670
EGTTPEKYLG
680
AEYMQSVGNM
690
RKCSTSRLLE
ACTFHKH
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016324 | apical plasma membrane |
| Cellular Component | GO:0009925 | basal plasma membrane |
| Cellular Component | GO:0009986 | cell surface |
| Cellular Component | GO:0005905 | clathrin-coated pit |
| Cellular Component | GO:0005769 | early endosome |
| Cellular Component | GO:0030139 | endocytic vesicle |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:1990712 | HFE-transferrin receptor complex |
| Cellular Component | GO:0005770 | late endosome |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0055037 | recycling endosome |
| Molecular Function | GO:0019899 | enzyme binding |
| Molecular Function | GO:0008199 | ferric iron binding |
| Molecular Function | GO:0008198 | ferrous iron binding |
| Molecular Function | GO:0034986 | iron chaperone activity |
| Molecular Function | GO:1990459 | transferrin receptor binding |
| Molecular Function | GO:0044325 | transmembrane transporter binding |
| Biological Process | GO:0019731 | antibacterial humoral response |
| Biological Process | GO:0007166 | cell surface receptor signaling pathway |
| Biological Process | GO:0071281 | cellular response to iron ion |
| Biological Process | GO:0006879 | intracellular iron ion homeostasis |
| Biological Process | GO:0006826 | iron ion transport |
| Biological Process | GO:0060586 | multicellular organismal-level iron ion homeostasis |
| Biological Process | GO:0030316 | osteoclast differentiation |
| Biological Process | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
| Biological Process | GO:0048260 | positive regulation of receptor-mediated endocytosis |
Reference
[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.