Search Results
Overview
| Uniprot ID | Q924X2 |
|---|---|
| Protein Name | Carnitine O-palmitoyltransferase 1, muscle isoform |
| Gene Name | Cpt1b |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 209 | YRMETLAKEFQDKTA |
| 214 | LAKEFQDKTAPRLQK |
| 321 | NTTRIPGKETDLLQH |
| 626 | MMKGSHKKQDLQDLF |
Function
Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion
Protein Sequence
10
MAEAHQAVAF
20
QFTVTPDGVD
30
FRLSREALRH
40
IYLSGINSWK
50
KRLIRIKNGI
60
LRGVYPGSPT
70
SWLVVVMATV
80
GSNYCKVDIS
90
MGLVDCIQRC
100
LPERYGHFGT
110
PQTEALLSMV
120
IFSTGVWATG
130
IFFFRQTLKL
140
LLSYHGWMFE
150
MHSKTSHATK
160
IWAICVRLLS
170
SRRPMLYSFQ
180
TSLPKLPVPS
190
VPATIHRYLD
200
SVRPLLDDEA
210
YYRMETLAKE
220
FQDKTAPRLQ
230
KYLVLKSWWA
240
TNYVSDWWEE
250
YVYLRSRSPL
260
MVNSNYYAMD
270
FVLIKNTNVQ
280
AARLGNAVHA
290
MIMYRRKLDR
300
EEIKPVMALG
310
MVPMCSYQME
320
RMFNTTRIPG
330
KETDLLQHLS
340
ESRHVAVYHK
350
GRFFKVWLYE
360
GSRLLKPRDL
370
EMQFQRILDD
380
PSPPQPGEEK
390
LAALTAGGRV
400
EWAEARQTFF
410
SSGKNKMSLD
420
AIERAAFFVT
430
LDEDSHCYNP
440
DDETSLSLYG
450
KALLHGNCYN
460
RWFDKSFTLI
470
SCKNGLLGLN
480
TEHSWADAPI
490
IGHLWEFVLG
500
TDTFHLGYTE
510
TGHCVGEPNT
520
TLPPPQRLPW
530
DIPEQCREAI
540
ENSYQVAKAL
550
ADDVELYCFQ
560
FLPFGKGLIK
570
KCRTSPDAFV
580
QIALQLAHFR
590
DKGKFCLTYE
600
ASMTRMFREG
610
RTETVRSCTN
620
ESAAFVQAMM
630
KGSHKKQDLQ
640
DLFRKASEKH
650
QNMYRLAMTG
660
AGIDRHLFCL
670
YIVSKYLGVS
680
SPFLAEVLSE
690
PWSLSTSQIP
700
QFQICMFDPK
710
QYPNHLGAGG
720
GFGPVADDGY
730
GVSYMIAGEN
740
TMFFHISSKY
750
SSSETNAQRF
760
GNHIRQALLD
770
IAELFKISKT
DS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005758 | mitochondrial intermembrane space |
| Cellular Component | GO:0005741 | mitochondrial outer membrane |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0004095 | carnitine O-palmitoyltransferase activity |
| Biological Process | GO:0009437 | carnitine metabolic process |
| Biological Process | GO:0006853 | carnitine shuttle |
| Biological Process | GO:0006635 | fatty acid beta-oxidation |
| Biological Process | GO:0006631 | fatty acid metabolic process |
| Biological Process | GO:0015909 | long-chain fatty acid transport |
| Biological Process | GO:0009637 | response to blue light |
Reference
[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.
[2] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.