Search Results
Overview
| Uniprot ID | Q92552 |
|---|---|
| Protein Name | Small ribosomal subunit protein mS27 |
| Gene Name | MRPS27 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 45 | HKWEAREKEHYCLAD |
Function
RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis (PubMed:22841715). Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain (PubMed:22841715). Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu) (PubMed:22841715). Involved also in positive regulation of cell proliferation and tumor cell growth (PubMed:28714366)
Protein Sequence
10
MAASIVRRGM
20
LLARQVVLPQ
30
LSPAGKRYLL
40
SSAYVDSHKW
50
EAREKEHYCL
60
ADLASLMDKT
70
FERKLPVSSL
80
TISRLIDNIS
90
SREEIDHAEY
100
YLYKFRHSPN
110
CWYLRNWTIH
120
TWIRQCLKYD
130
AQDKALYTLV
140
NKVQYGIFPD
150
NFTFNLLMDS
160
FIKKENYKDA
170
LSVVFEVMMQ
180
EAFEVPSTQL
190
LSLYVLFHCL
200
AKKTDFSWEE
210
ERNFGASLLL
220
PGLKQKNSVG
230
FSSQLYGYAL
240
LGKVELQQGL
250
RAVYHNMPLI
260
WKPGYLDRAL
270
QVMEKVAASP
280
EDIKLCREAL
290
DVLGAVLKAL
300
TSADGASEEQ
310
SQNDEDNQGS
320
EKLVEQLDIE
330
ETEQSKLPQY
340
LERFKALHSK
350
LQALGKIESE
360
GLLSLTTQLV
370
KEKLSTCEAE
380
DIATYEQNLQ
390
QWHLDLVQLI
400
QREQQQREQA
410
KQEYQAQKAA
KASA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0005763 | mitochondrial small ribosomal subunit |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0019843 | rRNA binding |
| Molecular Function | GO:0000049 | tRNA binding |
| Biological Process | GO:0008283 | cell population proliferation |
| Biological Process | GO:0032543 | mitochondrial translation |
| Biological Process | GO:0006417 | regulation of translation |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.