Search Results
Overview
| Uniprot ID | Q92777 |
|---|---|
| Protein Name | Synapsin-2 |
| Gene Name | SYN2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 114 | PAAARKAKVLLVVDE |
| 128 | EPHADWAKCFRGKKV |
| 134 | AKCFRGKKVLGDYDI |
| 243 | YKTLGGEKFPLIEQT |
| 318 | KYDIRVQKIGNNYKA |
| 441 | QPQSGTLKDPDSSKT |
Function
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. May play a role in noradrenaline secretion by sympathetic neurons (By similarity)
Protein Sequence
10
MMNFLRRRLS
20
DSSFIANLPN
30
GYMTDLQRPE
40
PQQPPPPPPP
50
GPGAASASAA
60
PPTASPGPER
70
RPPPASAPAP
80
QPAPTPSVGS
90
SFFSSLSQAV
100
KQTAASAGLV
110
DAPAPAPAAA
120
RKAKVLLVVD
130
EPHADWAKCF
140
RGKKVLGDYD
150
IKVEQAEFSE
160
LNLVAHADGT
170
YAVDMQVLRN
180
GTKVVRSFRP
190
DFVLIRQHAF
200
GMAENEDFRH
210
LIIGMQYAGL
220
PSINSLESIY
230
NFCDKPWVFA
240
QLVAIYKTLG
250
GEKFPLIEQT
260
YYPNHKEMLT
270
LPTFPVVVKI
280
GHAHSGMGKV
290
KVENHYDFQD
300
IASVVALTQT
310
YATAEPFIDS
320
KYDIRVQKIG
330
NNYKAYMRTS
340
ISGNWKTNTG
350
SAMLEQIAMS
360
DRYKLWVDTC
370
SEMFGGLDIC
380
AVKAVHGKDG
390
KDYIFEVMDC
400
SMPLIGEHQV
410
EDRQLITELV
420
ISKMNQLLSR
430
TPALSPQRPL
440
TTQQPQSGTL
450
KDPDSSKTPP
460
QRPPPQGGPG
470
QPQGMQPPGK
480
VLPPRRLPPG
490
PSLPPSSSSS
500
SSSSSSAPQR
510
PGGPTTHGDA
520
PSSSSSLAEA
530
QPPLAAPPQK
540
PQPHPQLNKS
550
QSLTNAFSFS
560
ESSFFRSSAN
570
EDEAKAETIR
580
SLRKSFASLF
SD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0098978 | glutamatergic synapse |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0014069 | postsynaptic density |
| Cellular Component | GO:0098685 | Schaffer collateral - CA1 synapse |
| Cellular Component | GO:0031201 | SNARE complex |
| Cellular Component | GO:0045202 | synapse |
| Cellular Component | GO:0030672 | synaptic vesicle membrane |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Biological Process | GO:0017156 | calcium-ion regulated exocytosis |
| Biological Process | GO:0007268 | chemical synaptic transmission |
| Biological Process | GO:0007269 | neurotransmitter secretion |
| Biological Process | GO:0050808 | synapse organization |
| Biological Process | GO:0097091 | synaptic vesicle clustering |
Reference
[1] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.