Search Results
Overview
| Uniprot ID | Q92805 |
|---|---|
| Protein Name | Golgin subfamily A member 1 |
| Gene Name | GOLGA1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 90 | NLQKIKEKLEIALEK |
Function
Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking. Mechanistically, captures transport vesicles arriving from endosomes via the protein TBC1D23 (PubMed:29084197, PubMed:38552021). Recognized vesicles are then tethered to the trans-Golgi before subsequent SNARE engagement and vesicle fusion. Selectively regulates E-cadherin transport from the trans-Golgi network in tubulovesicular carriers (PubMed:34969853)
Protein Sequence
10
MFAKLKKKIA
20
EETAVAQRPG
30
GATRIPRSVS
40
KESVASMGAD
50
SGDDFASDGS
60
SSREDLSSQL
70
LRRNEQIRKL
80
EARLSDYAEQ
90
VRNLQKIKEK
100
LEIALEKHQD
110
SSMRKFQEQN
120
ETFQANRAKM
130
AEGLALALAR
140
KDQEWSEKMD
150
QLEKEKNILT
160
AQLQEMKNQS
170
MNLFQRRDEM
180
DELEGFQQQE
190
LSKIKHMLLK
200
KEESLGKMEQ
210
ELEARTRELS
220
RTQEELMNSN
230
QMSSDLSQKL
240
EELQRHYSTL
250
EEQRDHVIAS
260
KTGAESKITA
270
LEQKEQELQA
280
LIQQLSIDLQ
290
KVTAETQEKE
300
DVITHLQEKV
310
ASLEKRLEQN
320
LSGEEHLQEL
330
LKEKTLAEQN
340
LEDTRQQLLA
350
ARSSQAKAIN
360
TLETRVRELE
370
QTLQASEEQL
380
QQSKGIVAAQ
390
ETQIQELAAA
400
NQESSHVQQQ
410
ALALEQQFLE
420
RTQALEAQIV
430
ALERTRAADQ
440
TTAEQGMRQL
450
EQENAALKEC
460
RNEYERSLQN
470
HQFELKKLKE
480
EWSQREIVSV
490
AMAQALEEVR
500
KQREEFQQQA
510
ANLTAIIDEK
520
EQNLREKTEV
530
LLQKEQEILQ
540
LERGHNSALL
550
QIHQLQAELE
560
ALRTLKAEEA
570
AVVAEQEDLL
580
RLRGPLQAEA
590
LSVNESHVTS
600
RAMQDPVFQL
610
PTAGRTPNGE
620
VGAMDLTQLQ
630
KEKQDLEQQL
640
LEKNKTIKQM
650
QQRMLELRKT
660
LQKELKIRPD
670
NELFEVREKP
680
GPEMANMAPS
690
VTNNTDLTDA
700
REINFEYLKH
710
VVLKFMSCRE
720
SEAFHLIKAV
730
SVLLNFSQEE
740
ENMLKETLEY
750
KMSWFGSKPA
760
PKGSIRPSIS
NPRIPWS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0001669 | acrosomal vesicle |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0000139 | Golgi membrane |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0005802 | trans-Golgi network |
| Molecular Function | GO:0140104 | molecular carrier activity |
| Biological Process | GO:0070633 | transepithelial transport |
Reference
[1] Cheng Z, Huang H, Li M, Chen Y. Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.. iScience 27(1):108645. 2024 Jan 19. PMID: 38155775.