Search Results
Overview
| Uniprot ID | Q92966 |
|---|---|
| Protein Name | snRNA-activating protein complex subunit 3 |
| Gene Name | SNAPC3 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 166 | MESHAIGKKPENSAD |
Function
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box
Protein Sequence
10
MAEGSRGGPT
20
CSGVGGRQDP
30
VSGSGGCNFP
40
EYELPELNTR
50
AFHVGAFGEL
60
WRGRLRGAGD
70
LSLREPPASA
80
LPGSQAADSD
90
REDAAVARDL
100
DCSLEAAAEL
110
RAVCGLDKLK
120
CLEDGEDPEV
130
IPENTDLVTL
140
GVRKRFLEHR
150
EETITIDRAC
160
RQETFVYEME
170
SHAIGKKPEN
180
SADMIEEGEL
190
ILSVNILYPV
200
IFHKHKEHKP
210
YQTMLVLGSQ
220
KLTQLRDSIR
230
CVSDLQIGGE
240
FSNTPDQAPE
250
HISKDLYKSA
260
FFYFEGTFYN
270
DKRYPECRDL
280
SRTIIEWSES
290
HDRGYGKFQT
300
ARMEDFTFND
310
LCIKLGFPYL
320
YCHQGDCEHV
330
IVITDIRLVH
340
HDDCLDRTLY
350
PLLIKKHWLW
360
TRKCFVCKMY
370
TARWVTNNDS
380
FAPEDPCFFC
390
DVCFRMLHYD
400
SEGNKLGEFL
410
AYPYVDPGTF
N
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0019185 | snRNA-activating protein complex |
| Molecular Function | GO:0003681 | bent DNA binding |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0000995 | RNA polymerase III general transcription initiation factor activity |
| Molecular Function | GO:0001006 | RNA polymerase III type 3 promoter sequence-specific DNA binding |
| Biological Process | GO:0009301 | snRNA transcription |
| Biological Process | GO:0042795 | snRNA transcription by RNA polymerase II |
| Biological Process | GO:0042796 | snRNA transcription by RNA polymerase III |
| Biological Process | GO:0006366 | transcription by RNA polymerase II |
| Biological Process | GO:0006383 | transcription by RNA polymerase III |
Reference
[1] Cheng Z, Huang H, Li M, Chen Y. Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.. iScience 27(1):108645. 2024 Jan 19. PMID: 38155775.