Search Results
Overview
| Uniprot ID | Q95274 |
|---|---|
| Protein Name | Thymosin beta-4 |
| Gene Name | TMSB4 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 12 | PDMAEIEKFDKSKLK |
| 26 | KKTETQEKNPLPSKE |
| 32 | EKNPLPSKETIEQEK |
| 39 | KETIEQEKQAGES** |
| 4 | ****MSDKPDMAEIE |
Function
Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Sequence
10
MSDKPDMAEI
20
EKFDKSKLKK
30
TETQEKNPLP
40
SKETIEQEKQ
AGES
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005856 | cytoskeleton |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003785 | actin monomer binding |
| Molecular Function | GO:0140311 | protein sequestering activity |
| Biological Process | GO:0007015 | actin filament organization |
| Biological Process | GO:0030334 | regulation of cell migration |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.