Search Results
Overview
| Uniprot ID | Q969I3 |
|---|---|
| Protein Name | Glycine N-acyltransferase-like protein 1 |
| Gene Name | GLYATL1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 121 | IRVATFSKSVKVEHS |
| 15 | HKLLALYKSLARSIP |
| 9 | ILLNNSHKLLALYKS |
| 98 | NCEIVNWKQRLQIQG |
Function
Acyltransferase which transfers an acyl group to the N-terminus of glutamine. Can use phenylacetyl-CoA as an acyl donor
Protein Sequence
10
MILLNNSHKL
20
LALYKSLARS
30
IPESLKVYGS
40
VYHINHGNPF
50
NMEVLVDSWP
60
EYQMVIIRPQ
70
KQEMTDDMDS
80
YTNVYRMFSK
90
EPQKSEEVLK
100
NCEIVNWKQR
110
LQIQGLQESL
120
GEGIRVATFS
130
KSVKVEHSRA
140
LLLVTEDILK
150
LNASSKSKLG
160
SWAETGHPDD
170
EFESETPNFK
180
YAQLDVSYSG
190
LVNDNWKRGK
200
NERSLHYIKR
210
CIEDLPAACM
220
LGPEGVPVSW
230
VTMDPSCEVG
240
MAYSMEKYRR
250
TGNMARVMVR
260
YMKYLRQKNI
270
PFYISVLEEN
280
EDSRRFVGQF
290
GFFEASCEWH
300
QWTCYPQNLV
PF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0047946 | glutamine N-acyltransferase activity |
| Molecular Function | GO:0047961 | glycine N-acyltransferase activity |
| Biological Process | GO:0006541 | glutamine metabolic process |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.