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Overview

Uniprot IDQ96A32
Protein NameMyosin regulatory light chain 11
Gene NameMYL11
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
112 KVLDPEGKGTIKKKF
118 GKGTIKKKFLEELLT
166 VITHGDAKDQE****
63 AMGRLNVKNEELDAM

Function

Myosin regulatory subunit that plays an essential role to maintain muscle integrity during early development (By similarity). Plays a role in muscle contraction (By similarity)

Protein Sequence

10 MAPKRAKRRT 20 VEGGSSSVFS 30 MFDQTQIQEF 40 KEAFTVIDQN 50 RDGIIDKEDL 60 RDTFAAMGRL 70 NVKNEELDAM 80 MKEASGPINF 90 TVFLTMFGEK 100 LKGADPEDVI 110 TGAFKVLDPE 120 GKGTIKKKFL 130 EELLTTQCDR 140 FSQEEIKNMW 150 AAFPPDVGGN 160 VDYKNICYVI THGDAKDQE

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005765 lysosomal membrane
Cellular Component GO:0005859 muscle myosin complex
Molecular Function GO:0005509 calcium ion binding
Molecular Function GO:0008307 structural constituent of muscle
Biological Process GO:0033275 actin-myosin filament sliding
Biological Process GO:0006936 muscle contraction
Biological Process GO:0060415 muscle tissue morphogenesis
Biological Process GO:0007519 skeletal muscle tissue development

Reference

[1] Lin Y, Chen M, Wang D, Yu Y, Chen R et al.. Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.. J Proteome Res 22(6):1712-1722. 2023 Jun 2. PMID: 37159428.