Search Results

Overview

Uniprot IDQ96A57
Protein NameTransmembrane protein 230
Gene NameTMEM230
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
16 ATGIPSSKVKYSRLS

Function

Involved in trafficking and recycling of synaptic vesicles

Protein Sequence

10 MMPSRTNLAT 20 GIPSSKVKYS 30 RLSSTDDGYI 40 DLQFKKTPPK 50 IPYKAIALAT 60 VLFLIGAFLI 70 IIGSLLLSGY 80 ISKGGADRAV 90 PVLIIGILVF 100 LPGFYHLRIA 110 YYASKGYRGY 120 SYDDIPDFDD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005776 autophagosome
Cellular Component GO:0030424 axon
Cellular Component GO:0005769 early endosome
Cellular Component GO:0012505 endomembrane system
Cellular Component GO:0005770 late endosome
Cellular Component GO:0016020 membrane
Cellular Component GO:0055037 recycling endosome
Cellular Component GO:0008021 synaptic vesicle
Cellular Component GO:0005802 trans-Golgi network
Biological Process GO:0098930 axonal transport
Biological Process GO:0048489 synaptic vesicle transport

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.

[2] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.