Search Results

Overview

Uniprot IDQ96AJ1
Protein NameClusterin-associated protein 1
Gene NameCLUAP1
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
335 LEERRLPKPQTAMEM

Function

Required for cilia biogenesis. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Key regulator of hedgehog signaling

Protein Sequence

10 MSFRDLRNFT 20 EMMRALGYPR 30 HISMENFRTP 40 NFGLVSEVLL 50 WLVKRYEPQT 60 DIPPDVDTEQ 70 DRVFFIKAIA 80 QFMATKAHIK 90 LNTKKLYQAD 100 GYAVKELLKI 110 TSVLYNAMKT 120 KGMEGSEIVE 130 EDVNKFKFDL 140 GSKIADLKAA 150 RQLASEITSK 160 GASLYDLLGM 170 EVELREMRTE 180 AIARPLEINE 190 TEKVMRIAIK 200 EILTQVQKTK 210 DLLNNVASDE 220 ANLEAKIEKR 230 KLELERNRKR 240 LETLQSVRPC 250 FMDEYEKTEE 260 ELQKQYDTYL 270 EKFQNLTYLE 280 QQLEDHHRME 290 QERFEEAKNT 300 LCLIQNKLKE 310 EEKRLLKSGS 320 NDDSDIDIQE 330 DDESDSELEE 340 RRLPKPQTAM 350 EMLMQGRPGK 360 RIVGTMQGGD 370 SDDNEDSEES 380 EIDMEDDDDE 390 DDDLEDESIS 400 LSPTKPNRRV 410 RKSEPLDESD NDF

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005813 centrosome
Cellular Component GO:0097546 ciliary base
Cellular Component GO:0097542 ciliary tip
Cellular Component GO:0005929 cilium
Cellular Component GO:0030991 intraciliary transport particle A
Cellular Component GO:0030992 intraciliary transport particle B
Cellular Component GO:0005815 microtubule organizing center
Cellular Component GO:0005654 nucleoplasm
Biological Process GO:0060271 cilium assembly
Biological Process GO:0035720 intraciliary anterograde transport

Reference

[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.