Search Results
Overview
| Uniprot ID | Q96BN6 |
|---|---|
| Protein Name | Primary cilium assembly protein FAM149B1 |
| Gene Name | FAM149B1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 381 | KLLDLDDKLLMRPGS |
Function
Involved in the localization of proteins to the cilium and cilium assembly. Indirectly regulates the signaling functions of the cilium, being required for normal SHH/smoothened signaling and proper development
Protein Sequence
10
MISRYTRKAV
20
PQSLELKGIT
30
KHALNHHPPP
40
EKLEEISPTS
50
DSHEKDTSSQ
60
SKSDITRESS
70
FTSADTGNSL
80
SAFPSYTGAG
90
ISTEGSSDFS
100
WGYGELDQNA
110
TEKVQTMFTA
120
IDELLYEQKL
130
SVHTKSLQEE
140
CQQWTASFPH
150
LRILGRQIIT
160
PSEGYRLYPR
170
SPSAVSASYE
180
TTLSQERDST
190
IFGIRGKKLH
200
FSSSYAHKAS
210
SIAKSSSFCS
220
MERDEEDSII
230
VSEGIIEEYL
240
AFDHIDIEEG
250
FHGKKSEAAT
260
EKQKLGYPPI
270
APFYCMKEDV
280
LAYVFDSVWC
290
KVVSCMEQLT
300
RSHWEGFASD
310
DESNVAVTRP
320
DSESSCVLSE
330
LHPLVLPRVP
340
QSKVLYITSN
350
PMSLCQASRH
360
QPNVNDLLVH
370
GMPLQPRNLS
380
LMDKLLDLDD
390
KLLMRPGSST
400
ILSTRNWPNR
410
AVEFSTSSLS
420
YTVQSTRRRN
430
PPPRTLHPIS
440
TSHSCAETPR
450
SVEEILRGAR
460
VPVAPDSLSS
470
PSPTPLSRNN
480
LLPPIGTAEV
490
EHVSTVGPQR
500
QMKPHGDSSR
510
AQSAVVDEPN
520
YQQPQERLLL
530
PDFFPRPNTT
540
QSFLLDTQYR
550
RSCAVEYPHQ
560
ARPGRGSAGP
570
QLHGSTKSQS
580
GGRPVSRTRQ
GP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005929 | cilium |
| Biological Process | GO:0060271 | cilium assembly |
| Biological Process | GO:0061512 | protein localization to cilium |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.