Search Results
Overview
| Uniprot ID | Q96BW9 |
|---|---|
| Protein Name | Phosphatidate cytidylyltransferase, mitochondrial |
| Gene Name | TAMM41 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 139 | GRLQKPVKIISVNED |
Function
Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol
Protein Sequence
10
MALQTLQSSW
20
VTFRKILSHF
30
PEELSLAFVY
40
GSGVYRQAGP
50
SSDQKNAMLD
60
FVFTVDDPVA
70
WHSKNLKKNW
80
SHYSFLKVLG
90
PKIITSIQNN
100
YGAGVYYNSL
110
IMCNGRLIKY
120
GVISTNVLIE
130
DLLNWNNLYI
140
AGRLQKPVKI
150
ISVNEDVTLR
160
SALDRNLKSA
170
VTAAFLMLPE
180
SFSEEDLFIE
190
IAGLSYSGDF
200
RMVVGEDKTK
210
VLNIVKPNIA
220
HFRELYGSIL
230
QENPQVVYKS
240
QQGWLEIDKS
250
PEGQFTQLMT
260
LPKTLQQQIN
270
HIMDPPGKNR
280
DVEETLFQVA
290
HDPDCGDVVR
300
LGLSAIVRPS
310
SIRQSTKGIF
320
TAGKSFGNPC
330
VTYLLTEWLP
340
HSWLQCKALY
350
LLGACEMLSF
360
DGHKLGYCSK
370
VQTGITAAEP
380
GGRTMSDHWQ
390
CCWKLYCPSE
400
FSETLPVCRV
410
FPSYCFIYQS
420
YRCIGLQKQQ
430
HLCSPSSSPS
440
LRQLLPSVLV
450
GYFCCYCHFS
KW
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0005759 | mitochondrial matrix |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0004605 | phosphatidate cytidylyltransferase activity |
| Biological Process | GO:0032049 | cardiolipin biosynthetic process |
| Biological Process | GO:0016024 | CDP-diacylglycerol biosynthetic process |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.