Search Results
Overview
| Uniprot ID | Q96C57 |
|---|---|
| Protein Name | Protein CUSTOS |
| Gene Name | CUSTOS |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 114 | PAKAKVQKVALEDDG |
| 89 | FRAHVAKKLGALLDS |
Function
Plays a role in the regulation of Wnt signaling pathway during early development
Protein Sequence
10
MAAPSGTVSD
20
SESSNSSSDA
30
EELERCREAA
40
MPAWGLEQRP
50
HVAGKPRAGA
60
ANSQLSTSQP
70
SLRHKVNEHE
80
QDGNELQTTP
90
EFRAHVAKKL
100
GALLDSFITI
110
SEAAKEPAKA
120
KVQKVALEDD
130
GFRLFFTSVP
140
GGREKEESPQ
150
PRRKRQPSSS
160
SEDSDEEWRR
170
CREAAVSASD
180
ILQESAIHSP
190
GTVEKEAKKK
200
RKLKKKAKKV
210
ASVDSAVAAT
220
TPTSMATVQK
230
QKSGELNGDQ
240
VSLGTKKKKK
250
AKKASETSPF
260
PPAKSATAIP
AN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005635 | nuclear envelope |
| Cellular Component | GO:0005730 | nucleolus |
| Biological Process | GO:0030178 | negative regulation of Wnt signaling pathway |
| Biological Process | GO:0060061 | Spemann organizer formation |
| Biological Process | GO:0016055 | Wnt signaling pathway |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.
[2] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.