Search Results
Overview
| Uniprot ID | Q96CX2 |
|---|---|
| Protein Name | BTB/POZ domain-containing protein KCTD12 |
| Gene Name | KCTD12 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 229 | RDAQADAKFRRVARI |
Function
Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity)
Protein Sequence
10
MALADSTRGL
20
PNGGGGGGGS
30
GSSSSSAEPP
40
LFPDIVELNV
50
GGQVYVTRRC
60
TVVSVPDSLL
70
WRMFTQQQPQ
80
ELARDSKGRF
90
FLDRDGFLFR
100
YILDYLRDLQ
110
LVLPDYFPER
120
SRLQREAEYF
130
ELPELVRRLG
140
APQQPGPGPP
150
PSRRGVHKEG
160
SLGDELLPLG
170
YSEPEQQEGA
180
SAGAPSPTLE
190
LASRSPSGGA
200
AGPLLTPSQS
210
LDGSRRSGYI
220
TIGYRGSYTI
230
GRDAQADAKF
240
RRVARITVCG
250
KTSLAKEVFG
260
DTLNESRDPD
270
RPPERYTSRY
280
YLKFNFLEQA
290
FDKLSESGFH
300
MVACSSTGTC
310
AFASSTDQSE
320
DKIWTSYTEY
VFCRE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Biological Process | GO:0008277 | regulation of G protein-coupled receptor signaling pathway |
| Cellular Component | GO:0045211 | postsynaptic membrane |
| Cellular Component | GO:0042734 | presynaptic membrane |
| Cellular Component | GO:0043235 | receptor complex |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0051260 | protein homooligomerization |
Reference
[1] Lin Y, Chen M, Wang D, Yu Y, Chen R et al.. Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.. J Proteome Res 22(6):1712-1722. 2023 Jun 2. PMID: 37159428.