Search Results
Overview
| Uniprot ID | Q96DY2 |
|---|---|
| Protein Name | Dynein regulatory complex subunit 10 |
| Gene Name | DRC10 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 231 | QIIDTLEKELAERMK |
Function
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes
Protein Sequence
10
MALDILAMAP
20
LYQAPAINRI
30
GPKTDPSKRP
40
ADPLKPLVLS
50
RTKLTTIEAK
60
RIMSILDEAI
70
YKVELVTLLS
80
YVASNREDME
90
GMLGEDVMRA
100
VREHEDLCQV
110
LLENVRCLKE
120
KERQLQEQKE
130
AEEEGWLRDR
140
LLSIELQKSS
150
LSPLMQQIKD
160
STKNVLRLLL
170
SNPQAARLLQ
180
MQTQGRSAEA
190
QNFIDSLIEL
200
RGFLFEKLLT
210
SPMEARDKAQ
220
FLQDISRQNS
230
NNQQIIDTLE
240
KELAERMKNR
250
NAEVEKENFV
260
IQELKNHLHQ
270
VLKFSENSLV
280
RTKQEAEKQQ
290
KADFRASQAR
300
VAKIQQEILQ
310
LQSQFYNLVM
320
ENREAEQALR
330
KKKYKVETEI
340
ENWIQKYDTE
350
MGEKQEELED
360
LDAVHREEKI
370
SLEELRRRHK
380
VLVGEFAQIR
390
EEREINSKKR
400
MEAEQEMVRM
410
VRAATLIQAL
420
WKGYLVRSLL
430
RSKKKRGKGK
440
AKDKEKGKQK
GKEKGKGKK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005930 | axoneme |
| Cellular Component | GO:0036064 | ciliary basal body |
| Biological Process | GO:0003341 | cilium movement |
| Biological Process | GO:0030317 | flagellated sperm motility |
Reference
[1] Yan M, Tu H, Tang S, Gai Z, Shi Q et al.. Lactylated Proteomic Analysis Reveals Functional Implications of Lysine Lactylation In Asthenozoospermia.. Mol Cell Proteomics 24(12):101439. 2025 Dec. PMID: 41192556.