Search Results
Overview
| Uniprot ID | Q96F86 |
|---|---|
| Protein Name | Enhancer of mRNA-decapping protein 3 |
| Gene Name | EDC3 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 105 | NGTGKFVKKPASSSS |
| 153 | MESLSQSKSFRRRHN |
Function
Binds single-stranded RNA. Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping. May play a role in spermiogenesis and oogenesis
Protein Sequence
10
MATDWLGSIV
20
SINCGDSLGV
30
YQGRVSAVDQ
40
VSQTISLTRP
50
FHNGVKCLVP
60
EVTFRAGDIT
70
ELKILEIPGP
80
GDNQHFGDLH
90
QTELGPSGAG
100
CQVGINQNGT
110
GKFVKKPASS
120
SSAPQNIPKR
130
TDVKSQDVAV
140
SPQQQQCSKS
150
YVDRHMESLS
160
QSKSFRRRHN
170
SWSSSSRHPN
180
QATPKKSGLK
190
NGQMKNKDDE
200
CFGDDIEEIP
210
DTDFDFEGNL
220
ALFDKAAVFE
230
EIDTYERRSG
240
TRSRGIPNER
250
PTRYRHDENI
260
LESEPIVYRR
270
IIVPHNVSKE
280
FCTDSGLVVP
290
SISYELHKKL
300
LSVAEKHGLT
310
LERRLEMTGV
320
CASQMALTLL
330
GGPNRLNPKN
340
VHQRPTVALL
350
CGPHVKGAQG
360
ISCGRHLANH
370
DVQVILFLPN
380
FVKMLESITN
390
ELSLFSKTQG
400
QQVSSLKDLP
410
TSPVDLVINC
420
LDCPENVFLR
430
DQPWYKAAVA
440
WANQNRAPVL
450
SIDPPVHEVE
460
QGIDAKWSLA
470
LGLPLPLGEH
480
AGRIYLCDIG
490
IPQQVFQEVG
500
INYHSPFGCK
FVIPLHSA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0036464 | cytoplasmic ribonucleoprotein granule |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0000932 | P-body |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0003729 | mRNA binding |
| Biological Process | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA |
| Biological Process | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA |
| Biological Process | GO:0000288 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay |
| Biological Process | GO:0033962 | P-body assembly |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.