Search Results
Overview
| Uniprot ID | Q96FJ2 |
|---|---|
| Protein Name | Dynein light chain 2, cytoplasmic |
| Gene Name | DYNLL2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 36 | MEKYNIEKDIAAYIK |
| 43 | KDIAAYIKKEFDKKY |
Function
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity)
Protein Sequence
10
MSDRKAVIKN
20
ADMSEDMQQD
30
AVDCATQAME
40
KYNIEKDIAA
50
YIKKEFDKKY
60
NPTWHCIVGR
70
NFGSYVTHET
80
KHFIYFYLGQ
VAILLFKSG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0097731 | 9+0 non-motile cilium |
| Cellular Component | GO:0097729 | 9+2 motile cilium |
| Cellular Component | GO:0005930 | axoneme |
| Cellular Component | GO:0005813 | centrosome |
| Cellular Component | GO:0097542 | ciliary tip |
| Cellular Component | GO:0005929 | cilium |
| Cellular Component | GO:0005868 | cytoplasmic dynein complex |
| Cellular Component | GO:0005856 | cytoskeleton |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0098978 | glutamatergic synapse |
| Cellular Component | GO:0001673 | male germ cell nucleus |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005874 | microtubule |
| Cellular Component | GO:0031475 | myosin V complex |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0098794 | postsynapse |
| Cellular Component | GO:0014069 | postsynaptic density |
| Cellular Component | GO:0036126 | sperm flagellum |
| Molecular Function | GO:0045505 | dynein intermediate chain binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0044877 | protein-containing complex binding |
| Molecular Function | GO:0097110 | scaffold protein binding |
| Biological Process | GO:0003341 | cilium movement |
| Biological Process | GO:0030317 | flagellated sperm motility |
| Biological Process | GO:0035721 | intraciliary retrograde transport |
| Biological Process | GO:0032388 | positive regulation of intracellular transport |
| Biological Process | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint |
Reference
[1] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.