Search Results
Overview
| Uniprot ID | Q96GA3 |
|---|---|
| Protein Name | Protein LTV1 homolog |
| Gene Name | LTV1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 381 | KQIRISSKTGIPLNV |
| 449 | RVEKKANKLAFKLEK |
Function
Essential for ribosome biogenesis
Protein Sequence
10
MPHRKKKPFI
20
EKKKAVSFHL
30
VHRSQRDPLA
40
ADESAPQRVL
50
LPTQKIDNEE
60
RRAEQRKYGV
70
FFDDDYDYLQ
80
HLKEPSGPSE
90
LIPSSTFSAH
100
NRREEKEETL
110
VIPSTGIKLP
120
SSVFASEFEE
130
DVGLLNKAAP
140
VSGPRLDFDP
150
DIVAALDDDF
160
DFDDPDNLLE
170
DDFILQANKA
180
TGEEEGMDIQ
190
KSENEDDSEW
200
EDVDDEKGDS
210
NDDYDSAGLL
220
SDEDCMSVPG
230
KTHRAIADHL
240
FWSEETKSRF
250
TEYSMTSSVM
260
RRNEQLTLHD
270
ERFEKFYEQY
280
DDDEIGALDN
290
AELEGSIQVD
300
SNRLQEVLND
310
YYKEKAENCV
320
KLNTLEPLED
330
QDLPMNELDE
340
SEEEEMITVV
350
LEEAKEKWDC
360
ESICSTYSNL
370
YNHPQLIKYQ
380
PKPKQIRISS
390
KTGIPLNVLP
400
KKGLTAKQTE
410
RIQMINGSDL
420
PKVSTQPRSK
430
NESKEDKRAR
440
KQAIKEERKE
450
RRVEKKANKL
460
AFKLEKRRQE
470
KELLNLKKNV
EGLKL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0030688 | preribosome, small subunit precursor |
| Biological Process | GO:0042274 | ribosomal small subunit biogenesis |
| Biological Process | GO:0000056 | ribosomal small subunit export from nucleus |
| Biological Process | GO:0042254 | ribosome biogenesis |
Reference
[1] Guo X, Ren X, Yan C, Huang H. Quantitative Proteomics Reveals the Role of Lysine Lactylation in Lenalidomide-Resistance in Multiple Myeloma Cells.. ACS Chem Biol 20(7):1728-1738. 2025 Jul 18. PMID: 40590393.
[2] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.