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Overview

Uniprot IDQ96GQ7
Protein NameProbable ATP-dependent RNA helicase DDX27
Gene NameDDX27
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
758 RGGNFKSKSRYKRRK

Function

Probable ATP-dependent RNA helicase. Component of the nucleolar ribosomal RNA (rRNA) processing machinery that regulates 3' end formation of ribosomal 47S rRNA (PubMed:25825154)

Protein Sequence

10 MLADLGLIGT 20 IGEDDEVPVE 30 PESDSGDEEE 40 EGPIVLGRRQ 50 KALGKNRSAD 60 FNPDFVFTEK 70 EGTYDGSWAL 80 ADVMSQLKKK 90 RAATTLDEKI 100 EKVRKKRKTE 110 DKEAKSGKLE 120 KEKEAKEGSE 130 PKEQEDLQEN 140 DEEGSEDEAS 150 ETDYSSADEN 160 ILTKADTLKV 170 KDRKKKKKKG 180 QEAGGFFEDA 190 SQYDENLSFQ 200 DMNLSRPLLK 210 AITAMGFKQP 220 TPIQKACIPV 230 GLLGKDICAC 240 AATGTGKTAA 250 FALPVLERLI 260 YKPRQAPVTR 270 VLVLVPTREL 280 GIQVHSVTRQ 290 LAQFCNITTC 300 LAVGGLDVKS 310 QEAALRAAPD 320 ILIATPGRLI 330 DHLHNCPSFH 340 LSSIEVLILD 350 EADRMLDEYF 360 EEQMKEIIRM 370 CSHHRQTMLF 380 SATMTDEVKD 390 LASVSLKNPV 400 RIFVNSNTDV 410 APFLRQEFIR 420 IRPNREGDRE 430 AIVAALLTRT 440 FTDHVMLFTQ 450 TKKQAHRMHI 460 LLGLMGLQVG 470 ELHGNLSQTQ 480 RLEALRRFKD 490 EQIDILVATD 500 VAARGLDIEG 510 VKTVINFTMP 520 NTIKHYVHRV 530 GRTARAGRAG 540 RSVSLVGEDE 550 RKMLKEIVKA 560 AKAPVKARIL 570 PQDVILKFRD 580 KIEKMEKDVY 590 AVLQLEAEEK 600 EMQQSEAQIN 610 TAKRLLEKGK 620 EAVVQEPERS 630 WFQTKEERKK 640 EKIAKALQEF 650 DLALRGKKKR 660 KKFMKDAKKK 670 GEMTAEERSQ 680 FEILKAQMFA 690 ERLAKRNRRA 700 KRARAMPEEE 710 PVRGPAKKQK 720 QGKKSVFDEE 730 LTNTSKKALK 740 QYRAGPSFEE 750 RKQLGLPHQR 760 RGGNFKSKSR YKRRK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005694 chromosome
Cellular Component GO:0005730 nucleolus
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0016887 ATP hydrolysis activity
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0003724 RNA helicase activity
Biological Process GO:0006364 rRNA processing

Reference

PMID: N/A