Search Results
Overview
| Uniprot ID | Q96ID5 |
|---|---|
| Protein Name | Immunoglobulin superfamily member 21 |
| Gene Name | IGSF21 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 69 | VTDGGTIKQKIFTFD |
Function
Involved in synaptic inhibition in the brain. Selectively regulates inhibitory presynaptic differentiation through interacting with presynaptic NRXN2
Protein Sequence
10
MRTAPSLRRC
20
VCLLLAAILD
30
LARGYLTVNI
40
EPLPPVVAGD
50
AVTLKCNFKT
60
DGRMREIVWY
70
RVTDGGTIKQ
80
KIFTFDAMFS
90
TNYSHMENYR
100
KREDLVYQST
110
VRLPEVRISD
120
NGPYECHVGI
130
YDRATREKVV
140
LASGNIFLNV
150
MAPPTSIEVV
160
AADTPAPFSR
170
YQAQNFTLVC
180
IVSGGKPAPM
190
VYFKRDGEPI
200
DAVPLSEPPA
210
ASSGPLQDSR
220
PFRSLLHRDL
230
DDTKMQKSLS
240
LLDAENRGGR
250
PYTERPSRGL
260
TPDPNILLQP
270
TTENIPETVV
280
SREFPRWVHS
290
AEPTYFLRHS
300
RTPSSDGTVE
310
VRALLTWTLN
320
PQIDNEALFS
330
CEVKHPALSM
340
PMQAEVTLVA
350
PKGPKIVMTP
360
SRARVGDTVR
370
ILVHGFQNEV
380
FPEPMFTWTR
390
VGSRLLDGSA
400
EFDGKELVLE
410
RVPAELNGSM
420
YRCTAQNPLG
430
STDTHTRLIV
440
FENPNIPRGT
450
EDSNGSIGPT
460
GARLTLVLAL
TVILELT
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030054 | cell junction |
| Cellular Component | GO:0009897 | external side of plasma membrane |
| Cellular Component | GO:0060077 | inhibitory synapse |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0098839 | postsynaptic density membrane |
| Cellular Component | GO:0042734 | presynaptic membrane |
| Biological Process | GO:0060074 | synapse maturation |
| Biological Process | GO:0099550 | trans-synaptic signaling, modulating synaptic transmission |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.