Search Results
Overview
| Uniprot ID | Q96IZ7 |
|---|---|
| Protein Name | Serine/Arginine-related protein 53 |
| Gene Name | RSRC1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 184 | LPPAEQAKARLQLVL |
| 253 | RSSKEVKKSVEPSEV |
Function
Has a role in alternative splicing and transcription regulation (PubMed:29522154). Involved in both constitutive and alternative pre-mRNA splicing. May have a role in the recognition of the 3' splice site during the second step of splicing
Protein Sequence
10
MGRRSSDTEE
20
ESRSKRKKKH
30
RRRSSSSSSS
40
DSRTYSRKKG
50
GRKSRSKSRS
60
WSRDLQPRSH
70
SYDRRRRHRS
80
SSSSSYGSRR
90
KRSRSRSRGR
100
GKSYRVQRSR
110
SKSRTRRSRS
120
RPRLRSHSRS
130
SERSSHRRTR
140
SRSRDRERRK
150
GRDKEKREKE
160
KDKGKDKELH
170
NIKRGESGNI
180
KAGLEHLPPA
190
EQAKARLQLV
200
LEAAAKADEA
210
LKAKERNEEE
220
AKRRKEEDQA
230
TLVEQVKRVK
240
EIEAIESDSF
250
VQQTFRSSKE
260
VKKSVEPSEV
270
KQATSTSGPA
280
SAVADPPSTE
290
KEIDPTSIPT
300
AIKYQDDNSL
310
AHPNLFIEKA
320
DAEEKWFKRL
330
IALRQERLMG
SPVA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005634 | nucleus |
| Biological Process | GO:0000380 | alternative mRNA splicing, via spliceosome |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
| Biological Process | GO:0006913 | nucleocytoplasmic transport |
| Biological Process | GO:0008380 | RNA splicing |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.
[2] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.