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Overview

Uniprot IDQ96KP1
Protein NameExocyst complex component 2
Gene NameEXOC2
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
197 LKRQANKKSEGSLAY

Function

Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane

Protein Sequence

10 MSRSRQPPLV 20 TGISPNEGIP 30 WTKVTIRGEN 40 LGTGPTDLIG 50 LTICGHNCLL 60 TAEWMSASKI 70 VCRVGQAKND 80 KGDIIVTTKS 90 GGRGTSTVSF 100 KLLKPEKIGI 110 LDQSAVWVDE 120 MNYYDMRTDR 130 NKGIPPLSLR 140 PANPLGIEIE 150 KSKFSQKDLE 160 MLFHGMSADF 170 TSENFSAAWY 180 LIENHSNTSF 190 EQLKMAVTNL 200 KRQANKKSEG 210 SLAYVKGGLS 220 TFFEAQDALS 230 AIHQKLEADG 240 TEKVEGSMTQ 250 KLENVLNRAS 260 NTADTLFQEV 270 LGRKDKADST 280 RNALNVLQRF 290 KFLFNLPLNI 300 ERNIQKGDYD 310 VVINDYEKAK 320 SLFGKTEVQV 330 FKKYYAEVET 340 RIEALRELLL 350 DKLLETPSTL 360 HDQKRYIRYL 370 SDLHASGDPA 380 WQCIGAQHKW 390 ILQLMHSCKE 400 GYVKDLKGNP 410 GLHSPMLDLD 420 NDTRPSVLGH 430 LSQTASLKRG 440 SSFQSGRDDT 450 WRYKTPHRVA 460 FVEKLTKLVL 470 SQLPNFWKLW 480 ISYVNGSLFS 490 ETAEKSGQIE 500 RSKNVRQRQN 510 DFKKMIQEVM 520 HSLVKLTRGA 530 LLPLSIRDGE 540 AKQYGGWEVK 550 CELSGQWLAH 560 AIQTVRLTHE 570 SLTALEIPND 580 LLQTIQDLIL 590 DLRVRCVMAT 600 LQHTAEEIKR 610 LAEKEDWIVD 620 NEGLTSLPCQ 630 FEQCIVCSLQ 640 SLKGVLECKP 650 GEASVFQQPK 660 TQEEVCQLSI 670 NIMQVFIYCL 680 EQLSTKPDAD 690 IDTTHLSVDV 700 SSPDLFGSIH 710 EDFSLTSEQR 720 LLIVLSNCCY 730 LERHTFLNIA 740 EHFEKHNFQG 750 IEKITQVSMA 760 SLKELDQRLF 770 ENYIELKADP 780 IVGSLEPGIY 790 AGYFDWKDCL 800 PPTGVRNYLK 810 EALVNIIAVH 820 AEVFTISKEL 830 VPRVLSKVIE 840 AVSEELSRLM 850 QCVSSFSKNG 860 ALQARLEICA 870 LRDTVAVYLT 880 PESKSSFKQA 890 LEALPQLSSG 900 ADKKLLEELL 910 NKFKSSMHLQ 920 LTCFQAASST MMKT

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Molecular Function GO:0030742 GTP-dependent protein binding
Molecular Function GO:0019901 protein kinase binding
Molecular Function GO:0031267 small GTPase binding
Biological Process GO:0006887 exocytosis
Biological Process GO:0006893 Golgi to plasma membrane transport
Biological Process GO:0090148 membrane fission
Biological Process GO:0000281 mitotic cytokinesis
Biological Process GO:0015031 protein transport
Biological Process GO:2000535 regulation of entry of bacterium into host cell
Biological Process GO:0006904 vesicle docking involved in exocytosis
Biological Process GO:0090522 vesicle tethering involved in exocytosis
Cellular Component GO:0000145 exocyst
Cellular Component GO:0090543 Flemming body
Cellular Component GO:0016020 membrane
Cellular Component GO:0005886 plasma membrane

Reference

[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.