Search Results
Overview
| Uniprot ID | Q96L21 |
|---|---|
| Protein Name | Ribosomal protein uL16-like |
| Gene Name | RPL10L |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 101 | FHVIRINKMLSCAGA |
| 42 | DLGRKKAKVDEFPLG |
Function
Testis-specific component of the ribosome, which is required for the transition from prophase to metaphase in male meiosis I (By similarity). Compensates for the inactivated X-linked RPL10 paralog during spermatogenesis (PubMed:12490704). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399, PubMed:25901680, PubMed:32669547). The male germ cell-specific ribosome displays a ribosomal polypeptide exit tunnel of distinct size and charge states compared with the classical ribosome (By similarity). It is responsible for regulating the biosynthesis and folding of a subset of male germ-cell-specific proteins that are essential for the formation of sperm (By similarity)
Protein Sequence
10
MGRRPARCYR
20
YCKNKPYPKS
30
RFCRGVPDAK
40
IRIFDLGRKK
50
AKVDEFPLGG
60
HMVSDEYEQL
70
SSEALEAARI
80
CANKYMVKSC
90
GRDGFHMRVR
100
LHPFHVIRIN
110
KMLSCAGADR
120
LQTGMRGAFG
130
KPQGTVARVH
140
IGQVIMSIRT
150
KLQNEEHVIE
160
ALRRAKFKFP
170
GRQKIHISKK
180
WGFTKFNADE
190
FEDMVAKKCL
200
IPDGCGVKYV
210
PSHGPLDKWR
VLHS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0022625 | cytosolic large ribosomal subunit |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005840 | ribosome |
| Molecular Function | GO:0003735 | structural constituent of ribosome |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:0002181 | cytoplasmic translation |
| Biological Process | GO:0007141 | male meiosis I |
| Biological Process | GO:0000027 | ribosomal large subunit assembly |
| Biological Process | GO:0007283 | spermatogenesis |
| Biological Process | GO:0006412 | translation |
Reference
PMID: N/A