Search Results

Overview

Uniprot ID	Q96M27
Protein Name	Protein PRRC1
Gene Name	PRRC1
Organism	Homo sapiens

Kla Sites from experimental identification

Position	Flanking peptide
234	KSVLDKTKHSVESMI
266	DIVVTSNKEVKVAAV
269	VTSNKEVKVAAVRDA

Function

May act as a regulator of the protein kinase A (PKA) activity during embryonic development

Protein Sequence

10 MMEESGIETT 20 PPGTPPPNPA 30 GLAATAMSST 40 PVPLAATSSF 50 SSPNVSSMES 60 FPPLAYSTPQ 70 PPLPPVRPSA 80 PLPFVPPPAV 90 PSVPPLVTSM 100 PPPVSPSTAA 110 AFGNPPVSHF 120 PPSTSAPNTL 130 LPAPPSGPPI 140 SGFSVGSTYD 150 ITRGHAGRAP 160 QTPLMPSFSA 170 PSGTGLLPTP 180 ITQQASLTSL 190 AQGTGTTSAI 200 TFPEEQEDPR 210 ITRGQDEASA 220 GGIWGFIKGV 230 AGNPMVKSVL 240 DKTKHSVESM 250 ITTLDPGMAP 260 YIKSGGELDI 270 VVTSNKEVKV 280 AAVRDAFQEV 290 FGLAVVVGEA 300 GQSNIAPQPV 310 GYAAGLKGAQ 320 ERIDSLRRTG 330 VIHEKQTAVS 340 VENFIAELLP 350 DKWFDIGCLV 360 VEDPVHGIHL 370 ETFTQATPVP 380 LEFVQQAQSL 390 TPQDYNLRWS 400 GLLVTVGEVL 410 EKSLLNVSRT 420 DWHMAFTGMS 430 RRQMIYSAAR 440 AIAGMYKQRL PPRTV

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005737	cytoplasm
Cellular Component	GO:0005794	Golgi apparatus
Molecular Function	GO:0042802	identical protein binding
Molecular Function	GO:0034237	protein kinase A regulatory subunit binding
Biological Process	GO:0010669	epithelial structure maintenance

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.

[2] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.

[3] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.