Search Results
Overview
| Uniprot ID | Q96N76 |
|---|---|
| Protein Name | Urocanate hydratase |
| Gene Name | UROC1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 41 | PSLSPVEKQLALRNA |
| 420 | RAGADVEKKGAGRTE |
| 517 | RILYSDQKGRVAIAV |
Function
No function data available.
Protein Sequence
10
MSSLQALCSG
20
LPLRPLPENR
30
GRQAGVPHAP
40
VRTPSLSPVE
50
KQLALRNALR
60
YFPPDVQELL
70
APEFAQELQL
80
YGHIYMYRFC
90
PDIEMRAYPI
100
EQYPCQTKVA
110
AAIMHMIMNN
120
LDPAVAQFPQ
130
ELVTYGGNGQ
140
VFSNWAQFWL
150
TMFYLSKMTE
160
EQTLVMYSGH
170
PLGLFPSSRS
180
APRLVITNGM
190
VIPNYSSRTE
200
YEKLFALGVT
210
MYGQMTAGSY
220
CYIGPQGIVH
230
GTVLTVLNAA
240
RRYLGIEDLA
250
GKVFVTSGLG
260
GMSGAQAKAA
270
VIVGCIGVIA
280
EVDKAALEKR
290
HRQGWLMEVT
300
DSLDRCIQRL
310
REARKKKEVL
320
SLGYHGNVVA
330
LWERLVHELD
340
TTGECLVDLG
350
SDQTSCHNPF
360
NGGYYPVQLS
370
FTEAQSLMAS
380
NPAVFKDLVQ
390
ESLRRQVSAI
400
NRLAEEKFFF
410
WDYGNAFLLE
420
AQRAGADVEK
430
KGAGRTEFRY
440
PSYVQHIMGD
450
IFSQGFGPFR
460
WVCTSGDPQD
470
LAVTDELATS
480
VLEEAIADGV
490
KVSVKLQYMD
500
NIRWIREAAR
510
HRLVVGSQAR
520
ILYSDQKGRV
530
AIAVAINQAI
540
ACRRIKAPVV
550
LSRDHHDVSG
560
TDSPFRETSN
570
IYDGSAFCAD
580
MAVQNFVGDA
590
CRGATWVALH
600
NGGGVGWGEV
610
INGGFGLVLD
620
GTPEAEGRAR
630
LMLSWDVSNG
640
VARRCWSGNQ
650
KAYEIICQTM
660
QENSTLVVTL
670
PHKVEDERVL
QQALQL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Molecular Function | GO:0016153 | urocanate hydratase activity |
| Biological Process | GO:0006548 | L-histidine catabolic process |
| Biological Process | GO:0019556 | L-histidine catabolic process to glutamate and formamide |
| Biological Process | GO:0019557 | L-histidine catabolic process to glutamate and formate |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.