Search Results
Overview
| Uniprot ID | Q96PE7 |
|---|---|
| Protein Name | Methylmalonyl-CoA epimerase, mitochondrial |
| Gene Name | MCEE |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 114 | PIAGFLQKNKAGGMH |
| 150 | RSLSEEVKIGAHGKP |
Function
Methylmalonyl-CoA epimerase involved in propionyl-CoA metabolism
Protein Sequence
10
MARVLKAAAA
20
NAVGLFSRLQ
30
APIPTVRASS
40
TSQPLDQVTG
50
SVWNLGRLNH
60
VAIAVPDLEK
70
AAAFYKNILG
80
AQVSEAVPLP
90
EHGVSVVFVN
100
LGNTKMELLH
110
PLGRDSPIAG
120
FLQKNKAGGM
130
HHICIEVDNI
140
NAAVMDLKKK
150
KIRSLSEEVK
160
IGAHGKPVIF
170
LHPKDCGGVL
VELEQA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005759 | mitochondrial matrix |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0004493 | methylmalonyl-CoA epimerase activity |
| Biological Process | GO:0046491 | L-methylmalonyl-CoA metabolic process |
| Biological Process | GO:0019626 | short-chain fatty acid catabolic process |
| Biological Process | GO:1901290 | succinyl-CoA biosynthetic process |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.