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Overview

Uniprot IDQ96QD9
Protein NameUAP56-interacting factor
Gene NameFYTTD1
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
309 RATLTYNKGGSRFVT

Function

Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4

Protein Sequence

10 MNRFGTRLVG 20 ATATSSPPPK 30 ARSNENLDKI 40 DMSLDDIIKL 50 NRKEGKKQNF 60 PRLNRRLLQQ 70 SGAQQFRMRV 80 RWGIQQNSGF 90 GKTSLNRRGR 100 VMPGKRRPNG 110 VITGLAARKT 120 TGIRKGISPM 130 NRPPLSDKNI 140 EQYFPVLKRK 150 ANLLRQNEGQ 160 RKPVAVLKRP 170 SQLSRKNNIP 180 ANFTRSGNKL 190 NHQKDTRQAT 200 FLFRRGLKVQ 210 AQLNTEQLLD 220 DVVAKRTRQW 230 RTSTTNGGIL 240 TVSIDNPGAV 250 QCPVTQKPRL 260 TRTAVPSFLT 270 KREQSDVKKV 280 PKGVPLQFDI 290 NSVGKQTGMT 300 LNERFGILKE 310 QRATLTYNKG GSRFVTVG

Gene Ontology

Classification GO ID Description
Cellular Component GO:0016607 nuclear speck
Cellular Component GO:0005654 nucleoplasm
Molecular Function GO:0003729 mRNA binding
Molecular Function GO:0003723 RNA binding
Biological Process GO:0006406 mRNA export from nucleus

Reference

PMID: N/A