Search Results
Overview
| Uniprot ID | Q96S94 |
|---|---|
| Protein Name | Cyclin-L2 |
| Gene Name | CCNL2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 439 | APRSAPYKGSEIRGS |
Function
Regulatory component of the cyclin-L-CDK11 complex that regulates transcription and pre-mRNA splicing (PubMed:18216018, PubMed:36104565, PubMed:38059508)
Protein Sequence
10
MAAAAAAAGA
20
AGSAAPAAAA
30
GAPGSGGAPS
40
GSQGVLIGDR
50
LYSGVLITLE
60
NCLLPDDKLR
70
FTPSMSSGLD
80
TDTETDLRVV
90
GCELIQAAGI
100
LLRLPQVAMA
110
TGQVLFQRFF
120
YTKSFVKHSM
130
EHVSMACVHL
140
ASKIEEAPRR
150
IRDVINVFHR
160
LRQLRDKKKP
170
VPLLLDQDYV
180
NLKNQIIKAE
190
RRVLKELGFC
200
VHVKHPHKII
210
VMYLQVLECE
220
RNQHLVQTSW
230
NYMNDSLRTD
240
VFVRFQPESI
250
ACACIYLAAR
260
TLEIPLPNRP
270
HWFLLFGATE
280
EEIQEICLKI
290
LQLYARKKVD
300
LTHLEGEVEK
310
RKHAIEEAKA
320
QARGLLPGGT
330
QVLDGTSGFS
340
PAPKLVESPK
350
EGKGSKPSPL
360
SVKNTKRRLE
370
GAKKAKADSP
380
VNGLPKGRES
390
RSRSRSREQS
400
YSRSPSRSAS
410
PKRRKSDSGS
420
TSGGSKSQSR
430
SRSRSDSPPR
440
QAPRSAPYKG
450
SEIRGSRKSK
460
DCKYPQKPHK
470
SRSRSSSRSR
480
SRSRERADNP
490
GKYKKKSHYY
500
RDQRRERSRS
510
YERTGRRYER
520
DHPGHSRHRR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0180038 | cyclin L-CDK11 complex |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0006397 | mRNA processing |
| Biological Process | GO:0042981 | regulation of apoptotic process |
| Biological Process | GO:0051726 | regulation of cell cycle |
| Biological Process | GO:0046605 | regulation of centrosome cycle |
| Biological Process | GO:0048024 | regulation of mRNA splicing, via spliceosome |
| Biological Process | GO:0043484 | regulation of RNA splicing |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
| Biological Process | GO:0008380 | RNA splicing |
Reference
PMID: N/A