Search Results

Overview

Uniprot IDQ96SI1
Protein NameBTB/POZ domain-containing protein KCTD15
Gene NameKCTD15
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
5 ***MPHRKERPSGSS

Function

During embryonic development, it is involved in neural crest formation (By similarity). Inhibits AP2 transcriptional activity by interaction with its activation domain (PubMed:23382213)

Protein Sequence

10 MPHRKERPSG 20 SSLHTHGSTG 30 TAEGGNMSRL 40 SLTRSPVSPL 50 AAQGIPLPAQ 60 LTKSNAPVHI 70 DVGGHMYTSS 80 LATLTKYPDS 90 RISRLFNGTE 100 PIVLDSLKQH 110 YFIDRDGEIF 120 RYVLSFLRTS 130 KLLLPDDFKD 140 FSLLYEEARY 150 YQLQPMVREL 160 ERWQQEQEQR 170 RRSRACDCLV 180 VRVTPDLGER 190 IALSGEKALI 200 EEVFPETGDV 210 MCNSVNAGWN 220 QDPTHVIRFP 230 LNGYCRLNSV 240 QVLERLFQRG 250 FSVAASCGGG 260 VDSSQFSEYV 270 LCREERRPQP 280 TPTAVRIKQE PLD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005634 nucleus
Molecular Function GO:0042802 identical protein binding
Molecular Function GO:0003714 transcription corepressor activity
Biological Process GO:0045892 negative regulation of DNA-templated transcription
Biological Process GO:0051260 protein homooligomerization

Reference

[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.