Search Results
Overview
| Uniprot ID | Q96TA1 |
|---|---|
| Protein Name | Protein Niban 2 |
| Gene Name | NIBAN2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 316 | MDQIITSKEHLASKI |
| 479 | VLERVLKKYDYDSSS |
| 620 | SEKRRRAKQVVSVVQ |
Function
May play a role in apoptosis suppression. May promote melanoma cell invasion in vitro
Protein Sequence
10
MGDVLSTHLD
20
DARRQHIAEK
30
TGKILTEFLQ
40
FYEDQYGVAL
50
FNSMRHEIEG
60
TGLPQAQLLW
70
RKVPLDERIV
80
FSGNLFQHQE
90
DSKKWRNRFS
100
LVPHNYGLVL
110
YENKAAYERQ
120
VPPRAVINSA
130
GYKILTSVDQ
140
YLELIGNSLP
150
GTTAKSGSAP
160
ILKCPTQFPL
170
ILWHPYARHY
180
YFCMMTEAEQ
190
DKWQAVLQDC
200
IRHCNNGIPE
210
DSKVEGPAFT
220
DAIRMYRQSK
230
ELYGTWEMLC
240
GNEVQILSNL
250
VMEELGPELK
260
AELGPRLKGK
270
PQERQRQWIQ
280
ISDAVYHMVY
290
EQAKARFEEV
300
LSKVQQVQPA
310
MQAVIRTDMD
320
QIITSKEHLA
330
SKIRAFILPK
340
AEVCVRNHVQ
350
PYIPSILEAL
360
MVPTSQGFTE
370
VRDVFFKEVT
380
DMNLNVINEG
390
GIDKLGEYME
400
KLSRLAYHPL
410
KMQSCYEKME
420
SLRLDGLQQR
430
FDVSSTSVFK
440
QRAQIHMREQ
450
MDNAVYTFET
460
LLHQELGKGP
470
TKEELCKSIQ
480
RVLERVLKKY
490
DYDSSSVRKR
500
FFREALLQIS
510
IPFLLKKLAP
520
TCKSELPRFQ
530
ELIFEDFARF
540
ILVENTYEEV
550
VLQTVMKDIL
560
QAVKEAAVQR
570
KHNLYRDSMV
580
MHNSDPNLHL
590
LAEGAPIDWG
600
EEYSNSGGGG
610
SPSPSTPESA
620
TLSEKRRRAK
630
QVVSVVQDEE
640
VGLPFEASPE
650
SPPPASPDGV
660
TEIRGLLAQG
670
LRPESPPPAG
680
PLLNGAPAGE
690
SPQPKAAPEA
700
SSPPASPLQH
710
LLPGKAVDLG
720
PPKPSDQETG
730
EQVSSPSSHP
740
ALHTTTEDSA
GVQTEF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005912 | adherens junction |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0045296 | cadherin binding |
| Molecular Function | GO:0003713 | transcription coactivator activity |
| Biological Process | GO:0032274 | gonadotropin secretion |
| Biological Process | GO:0043066 | negative regulation of apoptotic process |
| Biological Process | GO:0008285 | negative regulation of cell population proliferation |
| Biological Process | GO:2000279 | negative regulation of DNA biosynthetic process |
| Biological Process | GO:0045892 | negative regulation of DNA-templated transcription |
| Biological Process | GO:0045893 | positive regulation of DNA-templated transcription |
| Biological Process | GO:2000679 | positive regulation of transcription regulatory region DNA binding |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.
[3] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.