Search Results
Overview
| Uniprot ID | Q99525 |
|---|---|
| Protein Name | Histone H4-like protein type G |
| Gene Name | H4C7 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 13 | KAGKGLGKGGAKCHR |
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity)
Protein Sequence
10
MSVRGKAGKG
20
LGKGGAKCHR
30
KVLSDNIQGI
40
TKCTIRRLAR
50
HGGVKRILGL
60
IYEETRRVFK
70
VFLENVIWYA
80
VTNTEHAKRK
90
TVTAMAVVYV
LKRQGRTL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000786 | nucleosome |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:0030527 | structural constituent of chromatin |
| Biological Process | GO:0006334 | nucleosome assembly |
Reference
PMID: N/A