Search Results
Overview
| Uniprot ID | Q99583 |
|---|---|
| Protein Name | Max-binding protein MNT |
| Gene Name | MNT |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 227 | GTREVHNKLEKNRRA |
Function
Binds DNA as a heterodimer with MAX and represses transcription. Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'
Protein Sequence
10
MSIETLLEAA
20
RFLEWQAQQQ
30
QRAREEQERL
40
RLEQEREQEQ
50
KKANSLARLA
60
HTLPVEEPRM
70
EAPPLPLSPP
80
APPPAPPPPL
90
ATPAPLTVIP
100
IPVVTNSPQP
110
LPPPPPLPAA
120
AQPLPLAPRQ
130
PALVGAPGLS
140
IKEPAPLPSR
150
PQVPTPAPLL
160
PDSKATIPPN
170
GSPKPLQPLP
180
TPVLTIAPHP
190
GVQPQLAPQQ
200
PPPPTLGTLK
210
LAPAEEVKSS
220
EQKKRPGGIG
230
TREVHNKLEK
240
NRRAHLKECF
250
ETLKRNIPNV
260
DDKKTSNLSV
270
LRTALRYIQS
280
LKRKEKEYEH
290
EMERLAREKI
300
ATQQRLAELK
310
HELSQWMDVL
320
EIDRVLRQTG
330
QPEDDQASTS
340
TASEGEDNID
350
EDMEEDRAGL
360
GPPKLSHRPQ
370
PELLKSTLPP
380
PSTTPAPLPP
390
HPHPHPHSVA
400
LPPAHLPVQQ
410
QQPQQKTPLP
420
APPPPPAAPA
430
QTLVPAPAHL
440
VATAGGGSTV
450
IAHTATTHAS
460
VIQTVNHVLQ
470
GPGGKHIAHI
480
APSAPSPAVQ
490
LAPATPPIGH
500
ITVHPATLNH
510
VAHLGSQLPL
520
YPQPVAVSHI
530
AHTLSHQQVN
540
GTAGLGPPAT
550
VMAKPAVGAQ
560
VVHHPQLVGQ
570
TVLNPVTMVT
580
MPSFPVSTLK
LA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000785 | chromatin |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003682 | chromatin binding |
| Molecular Function | GO:0003700 | DNA-binding transcription factor activity |
| Molecular Function | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Molecular Function | GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0046983 | protein dimerization activity |
| Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| Molecular Function | GO:0000977 | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
| Biological Process | GO:0006366 | transcription by RNA polymerase II |
Reference
PMID: N/A