Search Results
Overview
| Uniprot ID | Q99963 |
|---|---|
| Protein Name | Endophilin-A3 |
| Gene Name | SH3GL3 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 20 | ASQLFSEKISGAEGT |
Function
Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity)
Protein Sequence
10
MSVAGLKKQF
20
HKASQLFSEK
30
ISGAEGTKLD
40
DEFLDMERKI
50
DVTNKVVAEI
60
LSKTTEYLQP
70
NPAYRAKLGM
80
LNTVSKIRGQ
90
VKTTGYPQTE
100
GLLGDCMLKY
110
GKELGEDSTF
120
GNALIEVGES
130
MKLMAEVKDS
140
LDINVKQTFI
150
DPLQLLQDKD
160
LKEIGHHLKK
170
LEGRRLDYDY
180
KKKRVGKIPD
190
EEVRQAVEKF
200
EESKELAERS
210
MFNFLENDVE
220
QVSQLAVFIE
230
AALDYHRQST
240
EILQELQSKL
250
QMRISAASSV
260
PRREYKPRPV
270
KRSSSELNGV
280
STTSVVKTTG
290
SNIPMDQPCC
300
RGLYDFEPEN
310
QGELGFKEGD
320
IITLTNQIDE
330
NWYEGMIHGE
340
SGFFPINYVE
VIVPLPQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0001669 | acrosomal vesicle |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0031901 | early endosome membrane |
| Cellular Component | GO:0098978 | glutamatergic synapse |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0099092 | postsynaptic density, intracellular component |
| Cellular Component | GO:0098845 | postsynaptic endosome |
| Cellular Component | GO:0098793 | presynapse |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0008289 | lipid binding |
| Molecular Function | GO:0030674 | protein-macromolecule adaptor activity |
| Biological Process | GO:0007417 | central nervous system development |
| Biological Process | GO:0006897 | endocytosis |
| Biological Process | GO:0061024 | membrane organization |
| Biological Process | GO:1900186 | negative regulation of clathrin-dependent endocytosis |
| Biological Process | GO:0045666 | positive regulation of neuron differentiation |
| Biological Process | GO:0007165 | signal transduction |
Reference
[1] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.