Search Results
Overview
| Uniprot ID | Q99JT1 |
|---|---|
| Protein Name | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial |
| Gene Name | Gatb |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 529 | RNPKAINKLIGLVRK |
Function
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
Protein Sequence
10
MAAPMLRLGF
20
PGRRWALTWL
30
DGGSRHRSGS
40
QTGPTSNWAR
50
RQSSVAQPSL
60
HTAQKPRKGE
70
HKWAAVVGLE
80
IHAQISSNSK
90
LFSGAQVCFA
100
APPNSLVSYF
110
DASLPGTLPV
120
LNRRCVEAAV
130
MTGLALNCHI
140
NKKSLFDRKH
150
YFYSDLPAGY
160
QITQQRLPIA
170
ANGHLTYCIY
180
LGKKPSQVTT
190
KTVRIKQIQL
200
EQDSGKSLHD
210
DLRSQTLIDL
220
NRAGIGLLEV
230
VLEPDLCCGE
240
EAALAVRELQ
250
LILQALGTSQ
260
ANMAEGQLRV
270
DANISVHHPG
280
EPLGVRTEVK
290
NLNSLRFLAK
300
AIDYEIQRQI
310
TELENGGEIL
320
NETRSFDYKL
330
GCTMPMRDKE
340
GKQDYRFMPE
350
PNLPPLVLYD
360
DTSLPRGADS
370
QQVINIDQLR
380
DMLPELPSAT
390
RERLVQQYGM
400
LPEHSFALLN
410
EVGLLEFFQN
420
VIKETRTEPK
430
KVTNWVLNTF
440
LCYLKQQNLA
450
VSESPVTPSA
460
LAELLNLLDR
470
KAISSSAAKQ
480
VFEELWKGEG
490
KTAAQIVSEQ
500
QLELMQDQEA
510
LEKLCQTTID
520
GHPQVVMDVK
530
KRNPKAINKL
540
IGLVRKASHS
550
RADPALIKKI
LERKLSL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030956 | glutamyl-tRNA(Gln) amidotransferase complex |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0050567 | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity |
| Biological Process | GO:0070681 | glutaminyl-tRNAGln biosynthesis via transamidation |
| Biological Process | GO:0032543 | mitochondrial translation |
Reference
[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.