Search Results
Overview
| Uniprot ID | Q99L13 |
|---|---|
| Protein Name | 3-hydroxyisobutyrate dehydrogenase, mitochondrial |
| Gene Name | Hibadh |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 124 | GILKKVKKGSLLIDS |
| 78 | PDVCKEFKEAGEQVA |
Function
No function data available.
Protein Sequence
10
MAASLGFRGA
20
ASGLWYWSGR
30
RRPVGSLAAV
40
CSRSMASKTP
50
VGFIGLGNMG
60
NPMAKNLMKH
70
GYPLILYDVF
80
PDVCKEFKEA
90
GEQVASSPAE
100
VAEKADRIIT
110
MLPSSMNAVE
120
VYSGANGILK
130
KVKKGSLLID
140
SSTIDPSVSK
150
ELAKEVEKMG
160
AVFMDAPVSG
170
GVGAARSGNL
180
TFMVGGVEDE
190
FAAAQELLEC
200
MGSNVVYCGA
210
VGTGQSAKIC
220
NNMLLAISMI
230
GTAEAMNLGI
240
RSGLDPKLLA
250
KILNMSSGRC
260
WSSDTYNPVP
270
GVMHGVPSSN
280
NYQGGFGTTL
290
MAKDLGLAQD
300
SATSTKTPIL
310
LGSLAHQIYR
320
MMCSKGYSKK
330
DFSSVFQYLR
EEEPF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0008442 | 3-hydroxyisobutyrate dehydrogenase activity |
| Molecular Function | GO:0051287 | NAD binding |
| Molecular Function | GO:0050661 | NADP binding |
| Biological Process | GO:0006574 | L-valine catabolic process |
Reference
[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.
[2] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.
[3] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.