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Overview

Uniprot IDQ99LY9
Protein NameNADH dehydrogenase [ubiquinone] iron-sulfur protein 5
Gene NameNdufs5
OrganismMus musculus

Kla Sites from experimental identification

Position Flanking peptide
8 MPFLDIQKKLGISLD

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Protein Sequence

10 MPFLDIQKKL 20 GISLDRHFMF 30 LSAEQPYKNA 40 ARCHAFEKEW 50 IECAHGIGGT 60 RAKKECKIEF 70 DDFEECLLRY 80 KTMRRMHDIK 90 KQREKLMKEG 100 KYTPPPHHSG REEPRP

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0005758 mitochondrial intermembrane space
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0045271 respiratory chain complex I
Biological Process GO:0009060 aerobic respiration
Biological Process GO:0032981 mitochondrial respiratory chain complex I assembly
Biological Process GO:0042776 proton motive force-driven mitochondrial ATP synthesis
Biological Process GO:0022904 respiratory electron transport chain

Reference

[1] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.