Search Results
Overview
| Uniprot ID | Q9BPX5 |
|---|---|
| Protein Name | Actin-related protein 2/3 complex subunit 5-like protein |
| Gene Name | ARPC5L |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 69 | RNSPVNTKNQAVKER |
Function
May function as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks
Protein Sequence
10
MARNTLSSRF
20
RRVDIDEFDE
30
NKFVDEQEEA
40
AAAAAEPGPD
50
PSEVDGLLRQ
60
GDMLRAFHAA
70
LRNSPVNTKN
80
QAVKERAQGV
90
VLKVLTNFKS
100
SEIEQAVQSL
110
DRNGVDLLMK
120
YIYKGFEKPT
130
ENSSAVLLQW
140
HEKALAVGGL
150
GSIIRVLTAR
KTV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0015629 | actin cytoskeleton |
| Cellular Component | GO:0005885 | Arp2/3 protein complex |
| Cellular Component | GO:0030863 | cortical cytoskeleton |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0005925 | focal adhesion |
| Cellular Component | GO:0098978 | glutamatergic synapse |
| Molecular Function | GO:0003779 | actin binding |
| Molecular Function | GO:0030674 | protein-macromolecule adaptor activity |
| Biological Process | GO:0034314 | Arp2/3 complex-mediated actin nucleation |
| Biological Process | GO:0016477 | cell migration |
| Biological Process | GO:0030833 | regulation of actin filament polymerization |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.