Search Results
Overview
| Uniprot ID | Q9BQI0 |
|---|---|
| Protein Name | Allograft inflammatory factor 1-like |
| Gene Name | AIF1L |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 13 | SNRFQGGKAFGLLKA |
Function
Actin-binding protein that promotes actin bundling. May neither bind calcium nor depend on calcium for function
Protein Sequence
10
MSGELSNRFQ
20
GGKAFGLLKA
30
RQERRLAEIN
40
REFLCDQKYS
50
DEENLPEKLT
60
AFKEKYMEFD
70
LNNEGEIDLM
80
SLKRMMEKLG
90
VPKTHLEMKK
100
MISEVTGGVS
110
DTISYRDFVN
120
MMLGKRSAVL
130
KLVMMFEGKA
140
NESSPKPVGP
150
PPERDIASLP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0015629 | actin cytoskeleton |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0005925 | focal adhesion |
| Cellular Component | GO:0032587 | ruffle membrane |
| Molecular Function | GO:0051015 | actin filament binding |
| Molecular Function | GO:0005509 | calcium ion binding |
| Biological Process | GO:0051017 | actin filament bundle assembly |
| Biological Process | GO:0097178 | ruffle assembly |
Reference
[1] Yang YH, Wang QC, Kong J, Yang JT, Liu JF. Global profiling of lysine lactylation in human lungs.. Proteomics 23(15):e2200437. 2023 Aug. PMID: 37170646.
[2] Cheng Z, Huang H, Li M, Chen Y. Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.. iScience 27(1):108645. 2024 Jan 19. PMID: 38155775.
[3] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.