Search Results

Overview

Uniprot ID	Q9BRD0
Protein Name	BUD13 homolog
Gene Name	BUD13
Organism	Homo sapiens

Kla Sites from experimental identification

Position	Flanking peptide
104	FRSSAKWKLLGGHNE
297	APERASSKTSPHWKE
418	RSQPPGKKAAHMYSG
605	FARLASKKAVEELAY

Function

Involved in pre-mRNA splicing as component of the activated spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs

Protein Sequence

10 MAAAPPLSKA 20 EYLKRYLSGA 30 DAGVDRGSES 40 GRKRRKKRPK 50 PGGAGGKGMR 60 IVDDDVSWTA 70 ISTTKLEKEE 80 EEDDGDLPVV 90 AEFVDERPEE 100 VKQMEAFRSS 110 AKWKLLGGHN 120 EDLPSNRHFR 130 HDTPDSSPRR 140 VRHGTPDPSP 150 RKDRHDTPDP 160 SPRRARHDTP 170 DPSPLRGARH 180 DSDTSPPRRI 190 RHDSSDTSPP 200 RRARHDSPDP 210 SPPRRPQHNS 220 SGASPRRVRH 230 DSPDPSPPRR 240 ARHGSSDISS 250 PRRVHNNSPD 260 TSRRTLGSSD 270 TQQLRRARHD 280 SPDLAPNVTY 290 SLPRTKSGKA 300 PERASSKTSP 310 HWKESGASHL 320 SFPKNSKYEY 330 DPDISPPRKK 340 QAKSHFGDKK 350 QLDSKGDCQK 360 ATDSDLSSPR 370 HKQSPGHQDS 380 DSDLSPPRNR 390 PRHRSSDSDL 400 SPPRRRQRTK 410 SSDSDLSPPR 420 RSQPPGKKAA 430 HMYSGAKTGL 440 VLTDIQREQQ 450 ELKEQDQETM 460 AFEAEFQYAE 470 TVFRDKSGRK 480 RNLKLERLEQ 490 RRKAEKDSER 500 DELYAQWGKG 510 LAQSRQQQQN 520 VEDAMKEMQK 530 PLARYIDDED 540 LDRMLREQER 550 EGDPMANFIK 560 KNKAKENKNK 570 KVRPRYSGPA 580 PPPNRFNIWP 590 GYRWDGVDRS 600 NGFEQKRFAR 610 LASKKAVEEL AYKWSVEDM

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005654	nucleoplasm
Cellular Component	GO:0005634	nucleus
Cellular Component	GO:0070274	RES complex
Cellular Component	GO:0071005	U2-type precatalytic spliceosome
Cellular Component	GO:0005684	U2-type spliceosomal complex
Molecular Function	GO:0003723	RNA binding
Biological Process	GO:0000398	mRNA splicing, via spliceosome
Biological Process	GO:1903241	U2-type prespliceosome assembly

Reference

[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.

[2] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.

[3] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.