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Overview

Uniprot IDQ9BRT3
Protein NameMigration and invasion enhancer 1
Gene NameMIEN1
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
47 LELASAVKEQYPGIE

Function

Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process

Protein Sequence

10 MSGEPGQTSV 20 APPPEEVEPG 30 SGVRIVVEYC 40 EPCGFEATYL 50 ELASAVKEQY 60 PGIEIESRLG 70 GTGAFEIEIN 80 GQLVFSKLEN 90 GGFPYEKDLI 100 EAIRRASNGE 110 TLEKITNSRP PCVIL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0009898 cytoplasmic side of plasma membrane
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0005886 plasma membrane
Biological Process GO:0006915 apoptotic process
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0051491 positive regulation of filopodium assembly

Reference

PMID: N/A