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Overview

Uniprot IDQ9BRT6
Protein NameProtein LLP homolog
Gene NameLLPH
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
125 AKAVKVAKGLAW***
34 SRLKSILKLDGDVLM
80 MKMETDIKRNKKTLL

Function

In hippocampal neurons, regulates dendritic and spine growth and synaptic transmission

Protein Sequence

10 MAKSLRSKWK 20 RKMRAEKRKK 30 NAPKEASRLK 40 SILKLDGDVL 50 MKDVQEIATV 60 VVPKPKHCQE 70 KMQCEVKDEK 80 DDMKMETDIK 90 RNKKTLLDQH 100 GQYPIWMNQR 110 QRKRLKAKRE 120 KRKGKSKAKA VKVAKGLAW

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005694 chromosome
Cellular Component GO:0005730 nucleolus
Molecular Function GO:0001099 basal RNA polymerase II transcription machinery binding
Molecular Function GO:0003723 RNA binding
Biological Process GO:0097484 dendrite extension
Biological Process GO:0060999 positive regulation of dendritic spine development

Reference

[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.