Search Results
Overview
| Uniprot ID | Q9BS86 |
|---|---|
| Protein Name | Zona pellucida-binding protein 1 |
| Gene Name | ZPBP |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 79 | AYVMLHQKSPHVLCV |
Function
Plays a role in acrosome compaction and sperm morphogenesis (PubMed:21911476). Is implicated in sperm-oocyte interaction during fertilization (By similarity)
Protein Sequence
10
MEAFALGPAR
20
RGRRRTRAAG
30
SLLSRAAILL
40
FISAFLVRVP
50
SSVGHLVRLP
60
RAFRLTKDSV
70
KIVGSTSFPV
80
KAYVMLHQKS
90
PHVLCVTQQL
100
RNAELIDPSF
110
QWYGPKGKVV
120
SVENRTAQIT
130
STGSLVFQNF
140
EESMSGIYTC
150
FLEYKPTVEE
160
IVKRLQLKYA
170
IYAYREPHYY
180
YQFTARYHAA
190
PCNSIYNISF
200
EKKLLQILSK
210
LLLDLSCEIS
220
LLKSECHRVK
230
MQRAGLQNEL
240
FFAFSVSSLD
250
TEKGPKRCTD
260
HNCEPYKRLF
270
KAKNLIERFF
280
NQQVEILGRR
290
AEQLPQIYYI
300
EGTLQMVWIN
310
RCFPGYGMNV
320
QQHPKCPECC
330
VICSPGSYNP
340
RDGIHCLQCN
350
SSLVYGAKTC
L
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0002080 | acrosomal membrane |
| Cellular Component | GO:0001669 | acrosomal vesicle |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0002199 | zona pellucida receptor complex |
| Biological Process | GO:0001675 | acrosome assembly |
| Biological Process | GO:0007339 | binding of sperm to zona pellucida |
Reference
[1] Yan M, Tu H, Tang S, Gai Z, Shi Q et al.. Lactylated Proteomic Analysis Reveals Functional Implications of Lysine Lactylation In Asthenozoospermia.. Mol Cell Proteomics 24(12):101439. 2025 Dec. PMID: 41192556.