Search Results
Overview
| Uniprot ID | Q9BSH4 |
|---|---|
| Protein Name | Translational activator of cytochrome c oxidase 1 |
| Gene Name | TACO1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 119 | CRSKHMPKSTIETAL |
| 132 | ALKMEKSKDTYLLYE |
| 170 | DIRHILNKNGGVMAV |
Function
Acts as a translational activator of mitochondrially-encoded cytochrome c oxidase 1
Protein Sequence
10
MSAWAAASLS
20
RAAARCLLAR
30
GPGVRAAPPR
40
DPRPSHPEPR
50
GCGAAPGRTL
60
HFTAAVPAGH
70
NKWSKVRHIK
80
GPKDVERSRI
90
FSKLCLNIRL
100
AVKEGGPNPE
110
HNSNLANILE
120
VCRSKHMPKS
130
TIETALKMEK
140
SKDTYLLYEG
150
RGPGGSSLLI
160
EALSNSSHKC
170
QADIRHILNK
180
NGGVMAVGAR
190
HSFDKKGVIV
200
VEVEDREKKA
210
VNLERALEMA
220
IEAGAEDVKE
230
TEDEEERNVF
240
KFICDASSLH
250
QVRKKLDSLG
260
LCSVSCALEF
270
IPNSKVQLAE
280
PDLEQAAHLI
290
QALSNHEDVI
HVYDNIE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0097177 | mitochondrial ribosome binding |
| Molecular Function | GO:0003729 | mRNA binding |
| Molecular Function | GO:0019843 | rRNA binding |
| Biological Process | GO:0070131 | positive regulation of mitochondrial translation |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.