Search Results
Overview
| Uniprot ID | Q9BT23 |
|---|---|
| Protein Name | LIM domain-containing protein 2 |
| Gene Name | LIMD2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 99 | FQQLFKSKGNYDEGF |
Function
Acts as an activator of the protein-kinase ILK, thereby regulating cell motility (PubMed:24590809)
Protein Sequence
10
MFQAAGAAQA
20
TPSHDAKGGG
30
SSTVQRSKSF
40
SLRAQVKETC
50
AACQKTVYPM
60
ERLVADKLIF
70
HNSCFCCKHC
80
HTKLSLGSYA
90
ALHGEFYCKP
100
HFQQLFKSKG
110
NYDEGFGRKQ
120
HKELWAHKEV
DPGTKTA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0015629 | actin cytoskeleton |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0051015 | actin filament binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Biological Process | GO:0051017 | actin filament bundle assembly |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.