Search Results
Overview
| Uniprot ID | Q9BTX1 |
|---|---|
| Protein Name | Nucleoporin NDC1 |
| Gene Name | NDC1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 673 | LQQFLEFKE****** |
Function
Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane
Protein Sequence
10
MATAVSRPCA
20
GRSRDILWRV
30
LGWRIVASIV
40
WSVLFLPICT
50
TVFIIFSRID
60
LFHPIQWLSD
70
SFSDLYSSYV
80
IFYFLLLSVV
90
IIIISIFNVE
100
FYAVVPSIPC
110
SRLALIGKII
120
HPQQLMHSFI
130
HAAMGMVMAW
140
CAAVITQGQY
150
SFLVVPCTGT
160
NSFGSPAAQT
170
CLNEYHLFFL
180
LTGAFMGYSY
190
SLLYFVNNMN
200
YLPFPIIQQY
210
KFLRFRRSLL
220
LLVKHSCVES
230
LFLVRNFCIL
240
YYFLGYIPKA
250
WISTAMNLHI
260
DEQVHRPLDT
270
VSGLLNLSLL
280
YHVWLCGVFL
290
LTTWYVSWIL
300
FKIYATEAHV
310
FPVQPPFAEG
320
SDECLPKVLN
330
SNPPPIIKYL
340
ALQDLMLLSQ
350
YSPSRRQEVF
360
SLSQPGGHPH
370
NWTAISRECL
380
NLLNGMTQKL
390
ILYQEAAATN
400
GRVSSSYPVE
410
PKKLNSPEET
420
AFQTPKSSQM
430
PRPSVPPLVK
440
TSLFSSKLST
450
PDVVSPFGTP
460
FGSSVMNRMA
470
GIFDVNTCYG
480
SPQSPQLIRR
490
GPRLWTSASD
500
QQMTEFSNPS
510
PSTSISAEGK
520
TMRQPSVIYS
530
WIQNKREQIK
540
NFLSKRVLIM
550
YFFSKHPEAS
560
IQAVFSDAQM
570
HIWALEGLSH
580
LVAASFTEDR
590
FGVVQTTLPA
600
ILNTLLTLQE
610
AVDKYFKLPH
620
ASSKPPRISG
630
SLVDTSYKTL
640
RFAFRASLKT
650
AIYRITTTFG
660
EHLNAVQASA
670
EHQKRLQQFL
EFKE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005635 | nuclear envelope |
| Cellular Component | GO:0031965 | nuclear membrane |
| Cellular Component | GO:0005643 | nuclear pore |
| Cellular Component | GO:0070762 | nuclear pore transmembrane ring |
| Molecular Function | GO:0030674 | protein-macromolecule adaptor activity |
| Molecular Function | GO:0017056 | structural constituent of nuclear pore |
| Biological Process | GO:0051028 | mRNA transport |
| Biological Process | GO:0051292 | nuclear pore complex assembly |
| Biological Process | GO:0051664 | nuclear pore localization |
| Biological Process | GO:0006999 | nuclear pore organization |
| Biological Process | GO:0006913 | nucleocytoplasmic transport |
| Biological Process | GO:0015031 | protein transport |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.