Search Results
Overview
| Uniprot ID | Q9BUL9 |
|---|---|
| Protein Name | Ribonuclease P protein subunit p25 |
| Gene Name | RPP25 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 184 | AAGEGSAKRSQPEPG |
Function
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:12003489, PubMed:16723659, PubMed:30454648). Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465)
Protein Sequence
10
MENFRKVRSE
20
EAPAGCGAEG
30
GGPGSGPFAD
40
LAPGAVHMRV
50
KEGSKIRNLM
60
AFATASMAQP
70
ATRAIVFSGC
80
GRATTKTVTC
90
AEILKRRLAG
100
LHQVTRLRYR
110
SVREVWQSLP
120
PGPTQGQTPG
130
EPAASLSVLK
140
NVPGLAILLS
150
KDALDPRQPG
160
YQPPNPHPGP
170
SSPPAAPASK
180
RSLGEPAAGE
190
GSAKRSQPEP
GVADEDQTA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030681 | multimeric ribonuclease P complex |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0000172 | ribonuclease MRP complex |
| Molecular Function | GO:0033204 | ribonuclease P RNA binding |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0006396 | RNA processing |
| Biological Process | GO:0006364 | rRNA processing |
| Biological Process | GO:0001682 | tRNA 5'-leader removal |
Reference
PMID: N/A